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SAT0524 Automated Breast Volume Scanner (ABVS), a New Automated Ultrasonic Device, is Useful to Examine Joint Injury in Patients with Rheumatoid Arthritis
  1. S.-Y. Kawashiri1,
  2. T. Suzuki1,
  3. Y. Nakashima1,
  4. Y. Horai1,
  5. A. Okada1,
  6. N. Iwamoto1,
  7. K. Ichinose1,
  8. M. Tamai1,
  9. K. Arima2,
  10. H. Nakamura1,
  11. T. Origuchi3,
  12. M. Uetani4,
  13. K. Aoyagi2,
  14. K. Eguchi5,
  15. A. Kawakami1
  1. 1Department Of Immunology And Rheumatology
  2. 2Department of Public Health
  3. 3Department of Health Sciences
  4. 4Department of Radiology and Radiation Research, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki
  5. 5Sasebo City General Hospital, Sasebo, Japan


Background Automated Breast Volume Scanner (ABVS) is an ultrasonic device to be developed for the automated scanning for mammary glands. ABVS is able to scan mammary gland automatically in a short time.

Objectives We have tried to explore the clinical application of ABVS toward the synovial lesion in patients with rheumatoid arthritis (RA).

Methods Thirteen active RA patients of mean 53 y.o., whose median disease duration 24 months and DAS28-ESR 6.02, were recruited. Patients gave their informed consent to be subjected to the protocol that was approved by the Institutional Review Board of Nagasaki University. We have examined total 130 metacarpophalangeal (MCP) joints as well as 26 wrist joints at dorsal sites by both ABVS (ACUSON S2000) and conventional ultrasonography (US) at the same day consecutively. ABVS was scanned in a water tank. Presence of synovial hypertrophy and bone erosion by gray-scale were examined by both methods, and the association of both methods was calculated by kappa coefficient.

Results The scanning time of ABVS was 2 min per patient and that of conventional US was 15 min per patient, respectively. ABVS detected synovial hypertrophy in 23 MCP joints and 20 wrist joints whereas conventional US detected synovial hypertrophy in 18 MCP joints and 20 wrist joints. Kappa coefficient of synovial hypertrophy was 0.80 in MCP joints and 1.00 in wrist joints, respectively. ABVS detected bone erosion in 8 MCP joints and 12 wrist joints whereas conventional US detected bone erosion in 5 MCP joints and 11 wrist joints. Kappa coefficient of bone erosion was 0.76 in MCP joints and 0.92 in wrist joints, respectively.

Conclusions Present data have shown a substantial agreement of ABVS with conventional US to find the synovial hypertrophy and bone erosion of wrist and finger joints in patients with RA. Since ABVS is able to scan the wrist and finger joints automatically in a short time, ABVS is a helpful new ultrasonic method to examine joint injury in patients with RA.

References Kawashiri SY, et al. The power Doppler ultrasonography score from 24 synovial sites or 6 simplified synovial sites, including the metacarpophalangeal joints, reflects the clinical disease activity and level of serum biomarkers in patients with rheumatoid arthritis. Rheumatology (Oxford) 2011; 50: 962-5.

Kawashiri SY, et al. Musculoskeletal ultrasonography assists the diagnostic performance of the 2010 classification criteria for rheumatoid arthritis. Mod Rheumatol. 2013;23:36-43.

Acknowledgements n.p.

Disclosure of Interest None Declared

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