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THU0565 Effectiveness of Collective Educational Intervention in the Management of Subcutaneous Biological Agents in Patients with Inflammatory Rheumatism
  1. L. Berard1,
  2. J.-F. Menard2,
  3. J. Benichou2,
  4. T. Lequerre2,
  5. O. Vittecoq2,
  6. S. Pouplin2
  1. 1Hôpital Jacques Monod, Le Havre
  2. 2CHU, Rouen, France


Background Educational programs are key-part of inflammatory rheumatism management. Nevertheless, few studies have assessed practical skills and safety use of subcutaneous biological agents.

Objectives To evaluate the impact of collective educational intervention (CEI) on good clinical practices and safety skills in patients with inflammatory rheumatism treated with subcutaneous biological agents.

Methods A self-questionnaire was developed to assess expected behaviours (injection skills, clinical items supervision, attitudes in front of different practical situations), knowledge of vaccinal status, required medical follow-up and need for information of patients with inflammatory rheumatism requiring subcutaneous biological agents. First administration was made in the hospital where every single patients receive individual education. Our interventional group was composed by voluntary patients at the first administration, who participate at one CEI performed 3 to 6 months later. The CEI lasted 2 hours by small groups including from 6 to 12 patients. Baseline self-questionnaire was filled by patients before the CEI, then good technical and clinical pratices were reminded by the educational team. This self-questionnaire was also filled at a one-year follow-up visit by control group and intervention group. We compared the one-year questionnaires for each arm.

Results From July 2009 to July 2012 : 64 and 305 patients, respectively included in the CEI and control groups, completed the one-year follow-up visit. At 12 months, the educational group showed significant better technical injection skills and better infectious risk management : pulmonary, urinary, cutaneous, Ear-Nose-Throat (ENT) (p<0,001), digestive (p= 0,008), surgical (p=0,009) and dental (p=0,015). The CEI group had significantly better knowledges of their vaccinal status compared to the control group. Additionnally, the CEI group improved significatively its required attitudes (pulmonary, cutaneous, urinary and ENT infectious risk management) at 12 months compared to baseline assessment.

Conclusions In this study, the collective educational intervention improvedsafety skills acquisition in biological treatments management, persisting at one-year follow-up compared to control group.


  1. Albano MG, et al. Characteristics and development of therapeutic pateint education in rheumatoid arthritis : analysis of the 2003-2008 literature. Joint Bone Spine 2010;77:405-10

  2. Riemsma R, et al. Patient education for adults with rheumatoid arthritis. Cochrane Database Syst Rev 2003;(2):CD003688

Disclosure of Interest None Declared

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