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Extended report
Prospective observational single-centre cohort study to evaluate the effectiveness of treating lupus nephritis with rituximab and mycophenolate mofetil but no oral steroids
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  • Published on:
    Response

    Dear Editor,

    Many thanks for the very interesting letter from Abud-Mendoza, highlighting their work in Mexico where they have successfully used rituximab in the treatment of both lupus nephritis and systemic lupus.
    Their initial report from 2006 [1] used rituximab as a treatment for refractory lupus nephritis and showed very detailed work on lymphocytes after rituximab administration. Supporting our data, th...

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    Conflict of Interest:
    None declared.
  • Published on:
    Are steroids required for therapy induction and relapses in lupus nephritis?
    • Carlos Abud-Mendoza, Proffesor
    • Other Contributors:
      • Carlos Abud-Mendoza, MD and Roberto Gonzalez Amaro MD

    Dear Editor,

    “A finger in the wound” is put by Condon et al. in their very interesting paper treating severe lupus nephritis with rituximab and mycophenolate, additionally to i.v. methyl-prednisolone, but not long-term oral steroids, achieving a good clinical response in most patients. 1

    Rheumatologists and nephrologists have the notion that glucocorticoids are the cornerstone for the treatment of autoimmune disea...

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    Conflict of Interest:
    None declared.