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Although we generally agree with Juanos-Iborra et al1 who noted that some of the most common manifestations of Erdheim–Chester disease (ECD) at time of onset (such as skeletal, constitutional or even neurological symptoms) may lack adequate specificity for a timely and prompt diagnosis, it is conceivable that the same manifestations, if unexplained, may often lead to …
Competing interests None.
Provenance and peer review Not commissioned; externally peer reviewed.
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