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The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males

Authors

  • Evangelos Evangelou Department of Hygiene and Epidemiology, University of Ioannina Medical School, University Campus, Ioannina, Greece Department of Twin Research and Genetic Epidemiology, St. Thomas’ Hospital, King's College, Lambeth Palace Road, London, UK PubMed articlesGoogle scholar articles
  • Ana M Valdes Department of Twin Research and Genetic Epidemiology, St. Thomas’ Hospital, King's College, Lambeth Palace Road, London, UK Academic Rheumatology, University of Nottingham, City Hospital Nottingham, Nottingham, UK PubMed articlesGoogle scholar articles
  • Martha C Castano-Betancourt Department of Internal Medicine, ErasmusMC, Rotterdam, The Netherlands The Netherlands Genomics Initiative-sponsored Netherlands Consortium for Healthy Aging (NGI-NCHA), Rotterdam/Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • M Doherty Academic Rheumatology, University of Nottingham, City Hospital Nottingham, Nottingham, UK PubMed articlesGoogle scholar articles
  • Sally Doherty Academic Rheumatology, University of Nottingham, City Hospital Nottingham, Nottingham, UK PubMed articlesGoogle scholar articles
  • Tonu Esko Estonian Genome Center, University of Tartu, Tartu, Estonia PubMed articlesGoogle scholar articles
  • Thorvaldur Ingvarsson Department of Orthopedic Surgery, Akureyri Hospital, Akureyri, Iceland Institution of Health Science, University of Akureyri, Akureyri, Iceland Faculty of Medicine, University of Iceland, Reykjavik, Iceland PubMed articlesGoogle scholar articles
  • John P A Ioannidis Department of Hygiene and Epidemiology, University of Ioannina Medical School, University Campus, Ioannina, Greece Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, USA PubMed articlesGoogle scholar articles
  • Margreet Kloppenburg Department of Rheumatology and Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Andres Metspalu Estonian Genome Center, University of Tartu, Tartu, Estonia PubMed articlesGoogle scholar articles
  • Evangelia E Ntzani Department of Hygiene and Epidemiology, University of Ioannina Medical School, University Campus, Ioannina, Greece PubMed articlesGoogle scholar articles
  • Kalliope Panoutsopoulou Wellcome Trust Sanger Institute, Hinxton, UK PubMed articlesGoogle scholar articles
  • P Eline Slagboom The Netherlands Genomics Initiative-sponsored Netherlands Consortium for Healthy Aging (NGI-NCHA), Rotterdam/Leiden, The Netherlands Department of Molecular Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Lorraine Southam Wellcome Trust Sanger Institute, Hinxton, UK PubMed articlesGoogle scholar articles
  • Tim D Spector Department of Twin Research and Genetic Epidemiology, St. Thomas’ Hospital, King's College, Lambeth Palace Road, London, UK PubMed articlesGoogle scholar articles
  • Unnur Styrkarsdottir deCODE Genetics, Reykjavik, Iceland PubMed articlesGoogle scholar articles
  • Kari Stefanson Faculty of Medicine, University of Iceland, Reykjavik, Iceland Department of Molecular Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • André G Uitterlinden Department of Internal Medicine, ErasmusMC, Rotterdam, The Netherlands The Netherlands Genomics Initiative-sponsored Netherlands Consortium for Healthy Aging (NGI-NCHA), Rotterdam/Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Margaret Wheeler Academic Rheumatology, University of Nottingham, City Hospital Nottingham, Nottingham, UK PubMed articlesGoogle scholar articles
  • Eleftheria Zeggini Wellcome Trust Sanger Institute, Hinxton, UK PubMed articlesGoogle scholar articles
  • Ingrid Meulenbelt The Netherlands Genomics Initiative-sponsored Netherlands Consortium for Healthy Aging (NGI-NCHA), Rotterdam/Leiden, The Netherlands Department of Molecular Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Joyce B van Meurs Department of Internal Medicine, ErasmusMC, Rotterdam, The Netherlands The Netherlands Genomics Initiative-sponsored Netherlands Consortium for Healthy Aging (NGI-NCHA), Rotterdam/Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • arcOGEN consortium, the TREAT-OA consortium
    Google scholar articles
  1. Correspondence to Dr Ana M Valdes, Academic Rheumatology, University of Nottingham, Clinical Sciences Bld, Nottingham City Hospital, Nottingham NG5 1PE, UK; ana.valdes{at}nottingham.ac.uk
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Citation

Evangelou E, Valdes AM, Castano-Betancourt C, et al
The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males

Publication history

  • Accepted February 24, 2013
  • First published March 16, 2013.
Online issue publication 
May 30, 2013

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