Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study

Mark C Genovese; Patrick Durez; Hanno B Richards; Jerzy Supronik; Eva Dokoupilova; Vadim Mazurov; Jacob A Aelion; Sang-Heon Lee; Christine E Codding; Herbert Kellner; Takashi Ikawa; Sophie Hugot; Shephard Mpofu

doi:10.1136/annrheumdis-2012-201601

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Clinical and epidemiological research

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Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study

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Mark C Genovese Department of Rheumatology, Stanford University, Palo Alto, California, USA PubMed articles Google scholar articles
Patrick Durez Université Catholique de Louvain, Brussels, Belgium PubMed articles Google scholar articles
Hanno B Richards Novartis Pharma AG, Basel, Switzerland PubMed articles Google scholar articles
Jerzy Supronik NZOZ Centrum Medyczne Artur Racewicz, Bialystok, Poland PubMed articles Google scholar articles
Eva Dokoupilova Medical Plus, Uherske Hradiste, Czech Republic PubMed articles Google scholar articles
Vadim Mazurov St. Petersburg State Medical Academy of Postgraduate Education, St Petersburg, Russia PubMed articles Google scholar articles
Jacob A Aelion The Arthritis Clinic, Jackson, Tennessee, USA PubMed articles Google scholar articles
Sang-Heon Lee Konkuk University Medical Center, Seoul, Republic of Korea PubMed articles Google scholar articles
Christine E Codding Health Research of Oklahoma, Oklahoma City, Oklahoma, USA PubMed articles Google scholar articles
Herbert Kellner Department of Rheumatology, Hospital Neuwittelsbach, Munich, Germany PubMed articles Google scholar articles
Takashi Ikawa Konan Yamate Clinic, Kobe, Hyogo, Japan PubMed articles Google scholar articles
Sophie Hugot Novartis Pharma AG, Basel, Switzerland PubMed articles Google scholar articles
Shephard Mpofu Novartis Pharma AG, Basel, Switzerland PubMed articles Google scholar articles

Correspondence to Dr Mark C Genovese, Division of Immunology and Rheumatology, Stanford University, 1000 Welch RD #203, Palo Alto, CA 94304, USA; genovese{at}stanford.edu

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Citation

Genovese MC, Durez P, Richards HB, et al

Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study

Annals of the Rheumatic Diseases 2013;72:863-869.

Publication history

Received February 28, 2012
Accepted May 20, 2012
First published June 23, 2012.

Online issue publication

May 10, 2013

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