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Axial spondyloarthritis: a new disease entity, not necessarily early ankylosing spondylitis
  1. Philip Cameron Robinson1,
  2. Bryan Paul Wordsworth2,
  3. John D Reveille3,
  4. Matthew A Brown1
  1. 1University of Queensland Diamantina Institute, Princess Alexandra Hospital,Brisbane Australia
  2. 2Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, Nuffield Orthopaedic Centre, University of Oxford, Headington, Oxford, UK
  3. 3Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas, USA
  1. Correspondence to Professor Matthew A Brown, University of Queensland Diamantina Institute, Princess Alexandra Hospital, Level 4, R Wing, Building 1, Woolloongabba, Brisbane, QLD 4102, Australia; matt.brown{at}


New classification criteria for axial spondyloarthritis have been developed with the goal of increasing sensitivity of criteria for early inflammatory spondyloarthritis. However these criteria substantially increase heterogeneity of the resulting disease group, reducing their value in both research and clinical settings. Further research to establish criteria based on better knowledge of the natural history of non-radiographic axial spondyloarthritis, its aetiopathogenesis and response to treatment is required. In the meantime the modified New York criteria for ankylosing spondylitis remain a very useful classification criteria set, defining a relatively homogenous group of cases for clinical use and research studies.

  • Spondyloarthritis
  • Ankylosing Spondylitis
  • Outcomes research

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