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Associations of CTX-II with biochemical markers of bone turnover raise questions on its tissue origin: data from CHECK, a cohort study of early osteoarthritis
  1. Willem E van Spil1,
  2. K Wiepke Drossaers-Bakker2,
  3. Floris PJG Lafeber1
  1. 1Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
  2. 2Arthritis Center Twente, Medical Spectrum Twente, Enschede, The Netherlands
  1. Correspondence to Willem E van Spil, Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Heidelberglaan 100, PO Box 85500, 3508 GA, Utrecht, The Netherlands; w.e.vanspil{at}umcutrecht.nl

Footnotes

  • Funding This study was supported by the Dutch Arthritis Association.

  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval CHECK received approval from the medical ethics committees of all involved medical centres.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement Additional unpublished data can be obtained from the corresponding author on request.

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Footnotes

  • Funding This study was supported by the Dutch Arthritis Association.

  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval CHECK received approval from the medical ethics committees of all involved medical centres.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement Additional unpublished data can be obtained from the corresponding author on request.

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