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AB1454-HPR Quality of life in patients with behÇet’s disease: the effects of disease severity and duration
  1. R.N. Demirtas1,
  2. S. Yasar Bilge2,
  3. C. Korkmaz2
  1. 1Physical Medicine and Rehabilitation, Eskisehir Osmangazi University, School of Medicine
  2. 2Rheumatology, Eskisehir Osmangazi University, School of Medicine, Eskisehir, Turkey


Background Behçet’s disease (BD) is a chronic, inflammatory, multisystemic vasculitic disorder with a wide spectrum of clinical presentations, BD may deteriorate of quality of life.

Objectives This study aimed to investigate effects of disease severity and duration on general health related quality of life in patients with Behçet’s Disease (BD)

Methods Patients fulfilling the International Study Group criteria for BD (ISGc) participated in our study. Disease severity was determined by related criteria.The quality of life was assessed by Short Form-36 (SF-36) questionnaire in 8 domains: physical function, role physical, bodily pain, general health, vitality, social function, role emotional, mental health. For usual clinical assessment, the routine assessment of patient index data (RAPID3) which is an index of three patient self-report measures-physical function, pain, and patient global estimate of status, was administered.

Results Thirty BD patients (15 female, 15 male) with a median age of 39,7±8,23 years were investigated in our study. The duration of BH was correlated to the scores of mental health domain of SF-36 (r = -,419, p<0,05) and RAPID3-pain (r =,374, p<0,05). The severity of BH was correlated to the body weight (r = -,389, p<0,05), the scores of physical function (r = -,401, p<0,05), bodily pain (r = -,406, p<0,05) domains of SF-36 and RAPID3-global status (r =,387, p<0,05). The correlations of severity and duration of BH and other scores of SF-36 and RAPID3 were poor (p>0,05). There were relationships between the domains scores of SF-36 and RAPID3 (p>0,05-p<0,001).

Conclusions In the light of these results, the severity and duration of BD negatively affect both physical and mental components of health related quality of life in patients with BD.

  1. Pincus T, Bergman MJ, Yazici YRAPID3-an index of physical function, pain, and global status as “vital signs” to improve care for people with chronic rheumatic diseases. Bull NYU Hosp Jt Dis. 2009;67(2):211-25.

  2. Bernabé E, Marcenes W, Mather J, Phillips C, Fortune F. Impact of Behçet’s syndrome on health-related quality of life: influence of the type and number of symptoms. Rheumatology (Oxford). 2010 Nov;49(11):2165-71. Epub 2010 Jul 30.

  3. Ertam I, Kitapcioglu G, Aksu K, Keser G, Ozaksar A, Elbi H, Unal I, Alper SQuality of life and its relation with disease severity in Behçet’s disease. Clin Exp Rheumatol. 2009 Mar-Apr;27(2 Suppl 53):S18-22.

Disclosure of Interest None Declared

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