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Susceptibility genes to systemic sclerosis (SSc) are substantially shared by other autoimmune diseases.1 UBE2L3, encoding a ubiquitin-conjugating enzyme, was associated with systemic lupus erythematosus (SLE)2 3 and rheumatoid arthritis (RA).4 In this study, we examined whether UBE2L3 is associated with SSc.
A case–control association study was performed on 391 Japanese patients and 1010 healthy controls recruited at Kanazawa University, the University of Tokyo, Institute of Rheumatology, Tokyo Women's Medical University and Sagamihara Hospital, National Hospital Organisation. All patients and …
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