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Extended report
A randomised controlled trial of ibuprofen, paracetamol or a combination tablet of ibuprofen/paracetamol in community-derived people with knee pain
  1. Michael Doherty1,
  2. Chris Hawkey2,
  3. Michael Goulder3,
  4. Iain Gibb4,
  5. Nicola Hill5,
  6. Sue Aspley6,
  7. Sandie Reader7
  1. 1Arthritis Research UK Pain Centre, Academic Rheumatology, Nottingham City Hospital, UK
  2. 2Nottingham Digestive Diseases Centre and Biomedical Research Unit, Queens Medical Centre, Nottingham, UK
  3. 3Worldwide Clinical Trials, Nottingham, UK
  4. 4Creativeclinical, Nottingham, UK
  5. 5Hill PharmaConsulting Ltd, Uttoxeter, UK
  6. 6Reckitt Benckiser Healthcare UK Ltd, Hull, UK
  7. 7Clearcut Clinical Consulting, Nottingham, UK
  1. Correspondence to Michael Doherty, Arthritis Research UK Pain Centre, Academic Rheumatology, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK; michael.doherty{at}nottingham.ac.uk

Footnotes

  • Funding This trial was sponsored by Reckitt Benckiser Healthcare International Ltd; study no: ISRCTN77199439. Editorial assistance was provided by Debra Scates, Elements Communications Ltd, supported by Reckitt Benckiser Healthcare International Ltd.

  • Competing interests MD received no personal financial reimbursement for the study, but has received honoraria for attending two advisory boards for Reckitt Benckiser. CH has received honoraria for attending advisory boards for Reckitt Benckiser. SA is currently an employee of Reckitt Benckiser and IG and SR were previously employed by Reckitt Benckiser and received salary and travel expenses. MG and NH have no conflict of interest relating to this publication.

  • Patient consent Obtained.

  • Ethics approval This study was conducted with the approval of the Southampton and South West Hampshire Research Ethics Committee (A) of the NHS National Research Ethics Service.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • Funding This trial was sponsored by Reckitt Benckiser Healthcare International Ltd; study no: ISRCTN77199439. Editorial assistance was provided by Debra Scates, Elements Communications Ltd, supported by Reckitt Benckiser Healthcare International Ltd.

  • Competing interests MD received no personal financial reimbursement for the study, but has received honoraria for attending two advisory boards for Reckitt Benckiser. CH has received honoraria for attending advisory boards for Reckitt Benckiser. SA is currently an employee of Reckitt Benckiser and IG and SR were previously employed by Reckitt Benckiser and received salary and travel expenses. MG and NH have no conflict of interest relating to this publication.

  • Patient consent Obtained.

  • Ethics approval This study was conducted with the approval of the Southampton and South West Hampshire Research Ethics Committee (A) of the NHS National Research Ethics Service.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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