Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI

Lukas Martin Wildi; Jean-Pierre Raynauld; Johanne Martel-Pelletier; André Beaulieu; Louis Bessette; Frédéric Morin; François Abram; Marc Dorais; Jean-Pierre Pelletier

doi:10.1136/ard.2010.140848

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Clinical and epidemiological research

Extended report

Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI

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	Abstract	Full	Pdf
Mar 2011	967	144	520
Apr 2011	476	127	271
May 2011	346	154	339
Jun 2011	192	123	176
Jul 2011	198	132	171
Aug 2011	130	96	139
Sep 2011	147	116	160
Oct 2011	144	133	92
Nov 2011	170	145	138
Dec 2011	158	102	95
Jan 2012	137	103	92
Feb 2012	113	65	72
Mar 2012	119	70	69
Apr 2012	125	71	66
May 2012	117	75	58
Jun 2012	92	81	52
Jul 2012	109	107	49
Aug 2012	131	112	55
Sep 2012	90	105	58
Oct 2012	160	161	71
Nov 2012	139	144	56
Dec 2012	85	93	46
Jan 2013	213	153	50
Feb 2013	152	102	35
Mar 2013	174	99	47
Apr 2013	356	91	45
May 2013	307	86	49
Jun 2013	154	51	32
Jul 2013	115	48	37
Aug 2013	98	59	23
Sep 2013	120	45	22
Oct 2013	114	61	48
Nov 2013	89	40	34
Dec 2013	81	43	34
Jan 2014	86	50	40
Feb 2014	106	59	37
Mar 2014	99	67	39
Apr 2014	102	56	29
May 2014	89	55	22
Jun 2014	89	39	26
Jul 2014	137	50	30
Aug 2014	83	43	24
Sep 2014	110	30	17
Oct 2014	62	48	17
Nov 2014	114	77	34
Dec 2014	106	37	25
Jan 2015	66	29	14
Feb 2015	113	51	23
Mar 2015	69	47	25
Apr 2015	71	59	33
May 2015	63	38	41
Jun 2015	45	27	11
Jul 2015	52	38	21
Aug 2015	52	45	25
Sep 2015	52	43	33
Oct 2015	45	32	33
Nov 2015	47	30	34
Dec 2015	88	35	17
Jan 2016	82	35	15
Feb 2016	85	23	19
Mar 2016	70	36	26
Apr 2016	59	32	25
May 2016	45	33	42
Jun 2016	60	15	25
Jul 2016	60	26	35
Aug 2016	44	41	27
Sep 2016	78	45	45
Oct 2016	58	44	28
Nov 2016	60	33	58
Dec 2016	44	23	17
Jan 2017	57	40	19
Feb 2017	23	32	24
Mar 2017	15	136	28
Apr 2017	32	67	42
May 2017	26	71	29
Jun 2017	53	68	78
Jul 2017	79	57	18
Aug 2017	102	61	32
Sep 2017	98	58	27
Oct 2017	121	55	30
Nov 2017	94	50	16
Dec 2017	93	51	28
Jan 2018	106	52	30
Feb 2018	76	49	39
Mar 2018	109	53	36
Apr 2018	116	74	25
May 2018	123	69	27
Jun 2018	102	60	27
Jul 2018	120	70	27
Aug 2018	127	69	29
Sep 2018	122	58	26
Oct 2018	107	61	30
Nov 2018	101	61	20
Dec 2018	78	42	21
Jan 2019	61	33	27
Feb 2019	41	30	19
Mar 2019	103	46	27
Apr 2019	72	50	31
May 2019	42	34	23
Jun 2019	70	41	16
Jul 2019	70	38	41
Aug 2019	43	23	17
Sep 2019	42	32	18
Oct 2019	53	27	26
Nov 2019	52	28	26
Dec 2019	51	33	23
Jan 2020	54	40	21
Feb 2020	56	44	22
Mar 2020	66	54	30
Apr 2020	73	64	31
May 2020	68	50	31
Jun 2020	66	56	30
Jul 2020	68	54	17
Aug 2020	62	44	20
Sep 2020	69	54	26
Oct 2020	78	68	26
Nov 2020	88	61	27
Dec 2020	94	71	17
Jan 2021	96	77	12
Feb 2021	62	56	16
Mar 2021	108	74	30
Apr 2021	88	67	25
May 2021	75	59	19
Jun 2021	52	50	21
Jul 2021	59	57	62
Aug 2021	52	51	20
Sep 2021	71	72	26
Oct 2021	81	69	29
Nov 2021	64	59	31
Dec 2021	54	36	19
Jan 2022	99	79	46
Feb 2022	51	46	26
Mar 2022	69	65	18
Apr 2022	101	83	22
May 2022	123	111	27
Jun 2022	79	75	20
Jul 2022	63	56	20
Aug 2022	79	67	13
Sep 2022	86	62	29
Oct 2022	63	59	11
Nov 2022	73	56	30
Dec 2022	50	43	8
Jan 2023	135	80	29
Feb 2023	167	81	36
Mar 2023	108	57	22
Apr 2023	76	65	30
May 2023	128	76	28
Total	15043	9235	6338

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