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2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis
  1. J Braun1,2,
  2. R van den Berg3,
  3. X Baraliakos1,
  4. H Boehm4,
  5. R Burgos-Vargas5,
  6. E Collantes-Estevez6,
  7. H Dagfinrud7,8,
  8. B Dijkmans9,
  9. M Dougados10,
  10. P Emery11,
  11. P Geher12,
  12. M Hammoudeh13,
  13. RD Inman14,
  14. M Jongkees15,
  15. MA Khan16,
  16. U Kiltz1,
  17. TK Kvien17,
  18. M Leirisalo-Repo18,
  19. WP Maksymowych19,
  20. I Olivieri20,
  21. K Pavelka21,
  22. J Sieper22,
  23. E Stanislawska-Biernat23,
  24. D Wendling24,
  25. S Özgocmen25,
  26. C van Drogen15,
  27. BJ van Royen26,
  28. D van der Heijde27
  1. 1Rheumazentrum Ruhrgebiet, Herne, Germany
  2. 2Ruhr-Universität Bochum, Bochum, Germany
  3. 3Department of Rheumatology, Leiden University Medical Center, The Netherlands
  4. 4Wirbelsäulenzentrum, Bad Berka, Germany
  5. 5Department of Rheumatology, Hospital General de México and Faculty of Medicine, Universidad Nacional Autónoma de México, Mexico
  6. 6University of Cordoba, Instituto Maimónides de Investigacion Biomédica de Córdoba (IMIBC), Spain
  7. 7Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
  8. 8University of Oslo, Oslo, Norway
  9. 9University of Amsterdam, The Netherlands
  10. 10Rheumatology B Department, Cochin Hospital, Descartes University Paris, France
  11. 11Section of Musculoskeletal Disease, University of Leeds, Leeds, UK
  12. 12University of Budapest, Budapest, Hungary
  13. 13Hamad Medical Corporation, Qatar
  14. 14University of Toronto, Toronto, Canada
  15. 15The Netherlands
  16. 16Case Western Reserve University, Cleveland, Ohio, USA
  17. 17Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Norway
  18. 18Department of Medicine, Division of Rheumatology, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
  19. 19University of Alberta, Edmonton, Alberta, Canada
  20. 20San Carlo Hospital, Potenza, Italy
  21. 21Institute and Clinic of Rheumatology, Charles University of Prague, Prague, Czech Republic
  22. 22Department. of Gastroenterology and Rheumatology, Universitaetsmedizin Charité, Berlin, Germany
  23. 23Institute of Rheumatology, Warsaw, Poland
  24. 24University of Besançon, Besançon, France
  25. 25Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Erciyes University, School of Medicine, Kayseri, Turkey
  26. 26Department of Orthopaedic Surgery, VU University Medical Center, Amsterdam, The Netherlands
  27. 27Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
  1. Correspondence to Professor Dr J Braun, Rheumazentrum Ruhrgebiet, Landgrafenstrasse 15, 44652 Herne, Germany; j.braun{at}


This first update of the ASAS/EULAR recommendations on the management of ankylosing spondylitis (AS) is based on the original paper, a systematic review of existing recommendations and the literature since 2005 and the discussion and agreement among 21 international experts, 2 patients and 2 physiotherapists in a meeting in February 2010. Each original bullet point was discussed in detail and reworded if necessary. Decisions on new recommendations were made — if necessary after voting. The strength of the recommendations (SOR) was scored on an 11-point numerical rating scale after the meeting by email. These recommendations apply to patients of all ages that fulfill the modified NY criteria for AS, independent of extra-articular manifestations, and they take into account all drug and non-drug interventions related to AS. Four overarching principles were introduced, implying that one bullet has been moved to this section. There are now 11 bullet points including 2 new ones, one related to extra-articular manifestations and one to changes in the disease course. With a mean score of 9.1 (range 8-10) the SOR was generally very good.

This paper is freely available online under the BMJ Journals unlocked scheme, see

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  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.