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Extended report
Phosphodiesterase 4 (PDE4) regulation of proinflammatory cytokine and chemokine release from rheumatoid synovial membrane
  1. Anne Crilly1,
  2. Susan E Robertson1,
  3. James H Reilly1,
  4. J Alastair Gracie1,
  5. Wen-Qi Lai2,
  6. Bernard P Leung1,2,
  7. Paul F Life3,
  8. Iain B McInnes1
  1. 1Institute of Infection, Immunity and Inflammation, Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, UK
  2. 2Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
  3. 3GlaxoSmithKline Medical Research Centre, Stevenage, UK
  1. Correspondence to Dr Anne Crilly, Level 4, McGregor Building, Western Infirmary, Glasgow G11 6NT, UK; anne.crilly{at}glasgow.ac.uk

Footnotes

  • Funding This work was supported by a research grant from GlaxoSmithKline Medical Research Centre.

  • Ethics approval This study was conducted with the approval of the local research ethical committee (Glasgow Royal Infirmary).

  • Competing interests None to declare.

  • Patient consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • Funding This work was supported by a research grant from GlaxoSmithKline Medical Research Centre.

  • Ethics approval This study was conducted with the approval of the local research ethical committee (Glasgow Royal Infirmary).

  • Competing interests None to declare.

  • Patient consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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