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Extended report
The impact of four dynamic, goal-steered treatment strategies on the 5-year outcomes of rheumatoid arthritis patients in the BeSt study
  1. Naomi B Klarenbeek1,
  2. Melek Güler-Yüksel1,
  3. Sjoerd M van der Kooij1,
  4. K Huub Han2,
  5. H Karel Ronday3,
  6. Pit J S M Kerstens4,
  7. Patrick E H Seys5,
  8. Tom W J Huizinga1,
  9. Ben A C Dijkmans4,6,
  10. Cornelia F Allaart1
  1. 1Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
  2. 2Department of Rheumatology, Maasstad Hospital, Rotterdam, The Netherlands
  3. 3Department of Rheumatology, Haga Hospital, The Hague, The Netherlands
  4. 4Department of Rheumatology, Jan van Breemen Institute, Amsterdam, The Netherlands
  5. 5Department of Rheumatology, Franciscus Hospital, Roosendaal, The Netherlands
  6. 6Department of Rheumatology, VU Medical Center, Amsterdam, The Netherlands
  1. Correspondence to Dr N B Klarenbeek, Department of Rheumatology, C-01-R, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands; n.b.klarenbeek{at}lumc.nl

Footnotes

  • Funding The trial was sponsored with a government grant from the Dutch College of Health Insurance Companies with additional sponsoring by Centocor Inc. and Schering-Plough Ltd. The sponsors were not involved in the study design, data collection, data analysis or preparation of the manuscript.

  • Competing interests TWJH, BACD and CFA received speakers' fees from various pharmaceutical companies (less than US$5000 per year).

  • Patient consent Obtained.

  • Ethics approval Ethics approval was obtained at the medical ethical committees of all participating centres.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • Funding The trial was sponsored with a government grant from the Dutch College of Health Insurance Companies with additional sponsoring by Centocor Inc. and Schering-Plough Ltd. The sponsors were not involved in the study design, data collection, data analysis or preparation of the manuscript.

  • Competing interests TWJH, BACD and CFA received speakers' fees from various pharmaceutical companies (less than US$5000 per year).

  • Patient consent Obtained.

  • Ethics approval Ethics approval was obtained at the medical ethical committees of all participating centres.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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