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Extended report
Lupus Atherosclerosis Prevention Study (LAPS)
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  • Published on:
    Corrected version of the e-letter "Selection bias may have blunted the effect of atorvastatin on the progression of atherosclerosis in systemic lupus erythematosus patients: Commentary on the Lupus Prevention Atherosclerosis Study (LAPS) "

    Dear editor,

    We read with interest the study by Petri et al. (1), which showed absence of effect of atorvastatin on the change in coronary artery calcium and carotideal intima media thickness in lupus patients treated for 2 years. Lupus was been considered a coronary heart disease (CHD) equivalent by some authors given the major increase of cardiovascular risk in this disease (2).

    The authors reported that patie...

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    Conflict of Interest:
    None declared.
  • Published on:
    About Lupus Atherosclerosis Prevention Study (LAPS)
    • JM Sabio, MD, PhD
    • Other Contributors:
      • N.Navarrete-Navarrete

    Dear Editor,

    We read with great interest the article of Petri et al [1] addressing the effect of atorvastatin 40 mg daily on subclinical atherosclerosis (ATS), systemic inflammation and disease activity in patients with systemic lupus erythematosus (SLE). Contrary to expectations, atorvastain had no effect on any of these parameters after 2 years of follup-up. Although these findings are clinically relevant, some issues...

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    Conflict of Interest:
    None declared.