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Dissemination and evaluation of the 3E initiative recommendations for use of methotrexate in rheumatic disorders: results of a study among 2233 rheumatologists
  1. L Gossec1,
  2. J W J Bijlsma2,
  3. C Bombardier3,
  4. H Canhão4,5,
  5. J Devlin6,
  6. C J Edwards7,
  7. V Hamuryudan8,
  8. T K Kvien9,
  9. B F Leeb10,
  10. E M Martín-Mola11,
  11. H Mielants12,
  12. U Müller-Ladner13,
  13. M Østergaard14,
  14. I A Pereira15,
  15. C Ramos-Remus16,
  16. J Zochling17,
  17. Maxime Dougados1
  1. 1Rheumatology B Department, Paris Descartes University, APHP, Cochin Hospital, Paris, France
  2. 2Department of Rheumatology and Clinical Immunology, University Medical Center, Utrecht, The Netherlands
  3. 3Rheumatology Division, Department of Medicine, University of Toronto, Ontario, Canada
  4. 4Rheumatology Research Unit, Instituto de Medicina Molecular, da Universidade de Lisboa, Lisbon, Portugal
  5. 5Serviço de Reumatologia e Doenças Ósseas Metabólicas, Hospital de Santa Maria, Lisbon, Portugal
  6. 6Waterford Regional Hospital, Waterford, Ireland
  7. 7Southampton University Hospital, Southampton, UK
  8. 8Division of Rheumatology, Department of Internal Medicine, Istanbul University, Istanbul, Turkey
  9. 9Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
  10. 10State Hospital Stockerau, Center for Rheumatology, Lower Austria, Stockerau, Austria
  11. 11Department of Rheumatology, Hospital Universitario La Paz, Universidad Autónoma, Madrid, Spain
  12. 12Department of Rheumatology, University of Gent, Gent, Belgium
  13. 13Department of Rheumatology and Clinical Immunology, Justus-Liebig-University, Gießen, Kerckhoff Clinic, Bad Nauheim, Germany
  14. 14Department of Rheumatology, Copenhagen University Hospitals at Hvidovre and Glostrup, Hvidovre, Denmark
  15. 15Division of Rheumatology, University Hospital of Santa Catarina, UFSC, Florianopolis, Brazil
  16. 16Unidad de Investigación en Enfermedades Cronico-Degenerativas, Guadalajara, Mexico
  17. 17Menzies Research Institute, University of Tasmania, Hobart, Australia
  1. Correspondence to Dr L Gossec, Rheumatology B Department, Paris Descartes University, UPRES-EA 4058, APHP, Cochin Hospital, Rhumatologie B4, 27 rue du Faubourg St Jacques, 75014 Paris, France; laure.gossec{at}

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Ten recommendations for the use of methotrexate were recently developed, based on published data and expert opinion in the 3E initiative1 (table 1). Clinical guidelines may induce small improvements both in processes and in the outcomes of care.2 However, if recommendations are to have effect, it is necessary after they have been published to facilitate their dissemination.3 In order to improve the implementation of these recommendations in daily practice, an initiative was performed in 2008 according to published methodology4 which aimed …

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  • Funding This work was supported by an unrestricted educational grant from Abbott pharmaceutical company.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.