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Association of a non-synonymous functional variant of the ITGAM gene with systemic sclerosis

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  • Funding This work was supported by GEN-FER from the Spanish Society of Rheumatology, SAF2009-11110 from the Spanish Ministry of Science, CTS-4977 and CTS-180 from junta de Andalucía, Orphan Disease program from EULAR, RETICS Program, RD08/0075 (RIER) from Instituto de Salud Carlos III (ISCIII), EUSTAR and the German Network of Systemic Sclerosis, VIDI laureate from the Dutch Association of Research (NWO) and Dutch Arthritis Foundation (National Reumafonds). TW was granted by DFG WI 1031/6.1. FDC was supported by Consejo Superior de Investigaciones Científicas (CSIC) through the programme JAE-DOC.

  • Patient consent Obtained.

  • Ethics approval Approvals were obtained from the local ethical committees of every participant centre.

  • Provenance and peer review Not commissioned; externally peer reviewed.