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KK and SYP contributed equally to this work and are joint first authors. CK and SCB contributed equally to this work.
Funding This work was supported by grants from the Research Program for New Drug Target Discovery (20090083335) and the Korean Healthcare Technology Research and Development Project (A080588).
Competing interests None.
Patient consent Obtained.
Ethics approval This study was approved by the Institutional Review Boards of Hanyang University Hospital for Rheumatic Diseases, Kyungpook National University Hospital, Eulji University Hospital, Ajou University Hospital, Yonsei University Severance Hospital, Chungnam National University Hospital and Korea Advanced Institute of Science and Technology.
Provenance and peer review Not commissioned; externally peer reviewed.
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