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Skin thickness progression rate: a predictor of mortality and early internal organ involvement in diffuse scleroderma
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  • Published on:
    Our response to questions raised by Drs Ugurlu and Seyahi

    We thank Drs Ugurlu and Seyahi for their comments and request for clarification regarding the development of the skin thickness progression rate. For the purpose of this study, we included only patients with early diffuse scleroderma at the time of the first Pittsburgh evaluation (<2 years duration). We defined diffuse cutaneous disease as skin thickening proximal to the elbows or knees (upper arms, thighs or trunk) o...

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    Conflict of Interest:
    None declared.
  • Published on:
    Skin thickness progression rate: a predictor of mortality and early internal organ involvement in diffuse scleroderma. Comment on the article by Domsic et al.
    • Serdal Ugurlu, Associate Professor
    • Other Contributors:
      • Emire Seyahi, MD

    To the editor, We read with interest the article by Domsic et al (1) in which they report that skin thickness progression rate (STPR) could predict mortality and early internal organ involvement in diffuse scleroderma (dSSc). There are few points that we would like to address: 1)Authors included only patients with diffuse skin involvement at the time of initial evaluation and measured STPR prospectively in 826 patients wit...

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    Conflict of Interest:
    None declared.