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Mesenchymal cells and subsets of T cells interact in the rheumatoid arthritis (RA) synovium leading to the local production of inflammatory cytokines. These high levels suggest a defect in the regulation of cytokine secretion, but the respective contribution of Th1 and Th17 cells remains to be clarified.
Mesenchymal stem cells (MSC) are known to play a role in the regulation of the immune response and are present …
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