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T cells
Elevated expression of the Th17 cytokine interleukin 22 in rheumatoid arthritis
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  1. M Schramm,
  2. J Leipe,
  3. H Schulze-Koops,
  4. A Skapenko
  1. Division of Rheumatology, Medizinische Poliklinik, University of Munich, Germany

https://doi.org/10.1136/ard.2010.129668b

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    Background and Objectives

    Interleukin 22 (IL22) is a pleiotropic cytokine with proinflammatory properties. It is primarily expressed by T helper 17 (Th17) cells and has recently been implicated in the pathogenesis of collagen-induced arthritis, a murine model of autoimmune polyarthritis. The authors were able to demonstrate a pathogenetically dominant role of Th17 cells and their signature cytokine IL17 in rheumatoid arthritis (RA) and psoriatic …

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