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Intravenous immunoglobulin promotes apoptosis of mature human B lymphocytes by using CD22 to modulate their antigen B cell receptor
  1. S Hillion,
  2. J-F Séité,
  3. J-O Pers,
  4. P Youinou
  1. EA 2216 ‘Immunologie et Pathologie’ and IFR 148 ScInBioS, Université de Brest, and Université Européenne de Bretagne, Brest, France

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Although widely used to treat inflammatory diseases, the mechanism by which intravenous immunoglobulin (IVIg) modulates immune function is not fully understood.

Materials and Methods

B cells from the blood of healthy volunteers and tonsils …

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