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Innate immunity
Alarmin interleukin 33 is overexpressed in psoriasis and induces ST2-dependent psoriasis-like dermatitis
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Psoriasis is an inflammatory skin disease characterised by hyperproliferation of keratinocytes, infiltration of inflammatory cells, impaired barrier function and alteration of tight junction proteins.
The interleukin 1 (IL1) family member IL33 has recently been described as an alarmin expressed in epithelial cells at body barriers, …
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