Article Text

Download PDFPDF

JKTBP (hnRNPDL) is a novel toll7/9 dependent target in humans and animal models of inflammatory rheumatic diseases
Free
  1. B Marklein1,
  2. Z Konthur2,
  3. A Cope3,
  4. M Shlomchik4,
  5. G Burmester1,
  6. K Skriner1
  1. 1Department of Rheumatology and Clinical Immunology, Humboldt University and Free University, Germany
  2. 2Department of Vertebrate Genomics, Max-Planck Institute for Molecular Genetics, Berlin, Germany
  3. 3Department of Rheumatology, King's College School of Medicine, London, UK
  4. 4Yale School of Medicine, New Haven, Connecticut, USA

Statistics from Altmetric.com

Objective

Autoimmune diseases are characterised and regularly diagnosed by the presence of autoantibodies to heterogeneous nuclear RNP (hnRNP) autoantigens. These proteins represent a group of autoantigens which are targeted by autoantibodies from patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and mixed connective tissue disease. The authors investigated a new member of the hnRNP family targeted by autoantibodies and tested a combination of hnRNPs in humans and …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.