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Fibrosis
Analysis of mononuclear cell subsets in dermis and blood of patients with systemic sclerosis by multicolour flow cytometry
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  1. Thomas Hügle,
  2. Venetia Bigley,
  3. Tony Holden,
  4. Jacob. M. van Laar
  1. Institute of Cellular Medicine, Musculoskeletal Research Group, Newcastle upon Tyne, Newcastle University, UK

https://doi.org/10.1136/ard.2010.129601c

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    Background

    Inflammation is a predominant feature in the early phase of systemic sclerosis (SSc) and putatively an important driver of fibrogenesis. Little is known about the homeostasis of monocytes, dendritic cells (DC), macrophages and lymphocytes in SSc skin and blood.

    Methods

    Multicolour flow cytometry of dermis and peripheral blood in seven patients with SSc and dermis …

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