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Sjögren's syndrome (SS): are increased serum levels of cytokine FMS-like tyrosine kinase 3 ligand (Flt3L) indicative of lymphoma?
  1. G J Tobón,
  2. V Devauchelle,
  3. P Youinou,
  4. J-O Pers
  1. EA 2216 ‘Immunologie et Pathologie’ and IFR 148 ScInBioS, Université de Brest, and Université Européenne de Bretagne, Brest, France

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Background

Flt3L, which is involved in the ontogenesis of B cells (particularly in their malignant proliferation in pSS) might contribute to the absolute excess of activated Bm2/germinal centre funder Bm2' B lymphocytes which characterises the peripheral blood (PB) pattern of these patients.

Objectives

Our aims were threefold: (1) Compare the …

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