Annals of the Rheumatic Diseases: 69 (Suppl 2)

Autoantibodies

HMGB1 containing nucleosomes from apoptotic cells induce inflammation and immune activation via TLR2 – implications for the etiopathogenesis of systemic lupus erythematosus (9 March, 2010) Free
V Urbonaviciute, B G Fürnrohr, S Meister, L Munoz, P Heyder, F De Marchis, M E Bianchi, C Kirschning, H Wagner, A A Manfredi, J R Kalden, G Schett, P Rovere-Querini, M Herrmann, R E Voll
Identification of a new citrullinated epitope on filaggrin for the early diagnosis of rheumatoid arthritis (9 March, 2010) Free
E Szarka, F Babos, A Magyar, F Hudecz, G Nagy, G Sármay
Natural autoantibodies reactive to glycosaminoglycans are disease state markers in rheumatoid arthritis and are associated with HLA (9 March, 2010) Free
B György, L Tóthfalusi, G Nagy, M Pásztói, P Géher, A Polgár, B Rojkovich, I Ujfalussy, P Misják, A Koncz, E Pozsonyi, G Füst, A Falus, E I Buzás
Upon contact with stimulated T cells, expression of peptidylarginine deiminase 2 and 4 is upregulated in human monocytes (9 March, 2010) Free
Sylvie Ferrari-Lacraz, Mireille Sebbag, Rachel Chicheportiche, Céline Foulquier, Guy Serre, Jean-Michel Dayer
Rheumatoid factor amplifies the macrophage secretion of TNFα induced by ACPA-citrullinated fibrinogen immune complexes (9 March, 2010) Free
L Laurent, C Clavel, J-L Pasquali, G Serre, M Sebbag
Anti-argonaute 2 (Ago2/Su) and –Ro antibodies are the common autoantibody specificities in primary anti-phospholipid syndrome (PAPS) (9 March, 2010) Free
A Ceribelli, I Cavazzana, F Franceschini, A Tincani, B A Pauley, J Y F Chan, E K L Chan, M Satoh
Structural insights into antigenicity of Ro/La ribonucleoprotein: SLE related epitopes are cryptic, masked by hY1 RNA (9 March, 2010) Free
J G Routsias, N C Kyriakidis, S Kotsakis, A G Tzioufas
JKTBP (hnRNPDL) is a novel toll7/9 dependent target in humans and animal models of inflammatory rheumatic diseases (9 March, 2010) Free
B Marklein, Z Konthur, A Cope, M Shlomchik, G Burmester, K Skriner
Cellular factor XIII and peptidylarginine deiminase-catalysed citrullination in rheumatoid arthritis (9 March, 2010) Free
B Roth, F Wollheim, P Stenberg
Identification of specific citrullination sites on fibrinogen in RA (9 March, 2010) Free
E Ossipova, V Malmström, A I Catrina, L Klareskog, R Zubarev, P-J Jakobsson
Systemic sclerosis as prototypic disease with high levels of functional antibodies against angiotensin II type-1 and endothelin-1 type A receptor strongly predicting prognosis (9 March, 2010) Free
G Riemekasten, A Philippe, I Lukitsch, T Slowinski, M Näther
Detection of genuine anti-citrullinated protein antibodies in mice reveals their presence in BALB/c but not DBA/1 and SJL mice hyperimmunised with citrullinated collagen (9 March, 2010) Free
T Cantaert, C A Teitsma, P P Tak, D L Baeten
The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in seropositive arthralgia patients (9 March, 2010) Free
L A van de Stadt, A van der Horst, M de Koning, W H Bos, G J Wolbink, R J van de Stadt, G J M Pruijn, B A C Dijkmans, D van Schaardenburg, D Hamann
SSA and SSB antibodies are important in the formation of circulating immune complexes in SLE (9 March, 2010) Free
E Åhlin, L Mathsson, M-L Eloranta, L Rönnblom, J Rönnelid
Comparative study between swedish and sudanese RA patients (9 March, 2010) Free
A I Elshafie, E Åhlin, S A Norein, K E Khalafalla, M Al-Edreese, E M Elagib, M A M Nur, J Rönnelid
Anti-citrullinated protein antibodies have a low avidity compared to antibodies against recall-antigens (9 March, 2010) Free
P Suwannalai, H U Scherer, D van der Woude, A Ioan-Facsinay, C M Jol-van der Zijde, M J van Tol, T W J Huizinga, R E M Toes, L A Trouw
Toll-like receptor 9 (TLR9) controls B-cell differentiation in salivary glands (SG) of patients with Sjögren's syndrome (SS) (9 March, 2010) Free
C Jamin, J-E Alard, J-O Pers, P Youinou
A gene–environment interaction between HLA SE alleles and smoking affects the reactivity of ACPA to various citrullinated antigens (9 March, 2010) Free
D van der Woude, W G Alemayehu, N A Daha, W Verduyn, R R P de Vries, J J Houwing-Duistermaat, T W J Huizinga, R E M Toes
Anti-CCP antibodies are a collection of ACPA that are cross-reactive to multiple citrullinated antigens (9 March, 2010) Free
A Ioan-Facsinay, H el-Bannoudi, H U Scherer, D van der Woude, H A Ménard, M Lora, L A Trouw, T W J Huizinga, R E M Toes
Prevalence of Toxoplasma antibodies among patients with various autoimmune diseases (9 March, 2010) Free
J Petríková, N Agmon-Levin, Y Shapira, O Barzilai, M Ram, B Gilburd, C Selmi, B Nicola, B Larida, M E Gershwin, G Valentini, M Matucci-Cerini, J-M Anaja, B-S P Katz, M Blank, Y Shoenfeld
Anti-apolipoprotein A-1 autoantibodies as an independent cardiovascular prognostic marker affecting basal heart rate in myocardial infarction (9 March, 2010) Free
N Vuilleumier, M F Rossier, S Pagano, M Python, E Charbonney, R Nkoulou, R James, G Reber, F Mach, P Roux-Lombard
Anti-Th/To antibodies in Italian scleroderma patients: clinical and immunological correlations and comparison with patients with anti-centromere antibodies (9 March, 2010) Free
A Ceribelli, I Cavazzana, P Airò, A Tincani, F Franceschini, B A Pauley, E K L Chan, M Satoh
Myositis associated autoantibodies detected using a novel recombinant protein blotting: clinical associations (9 March, 2010) Free
P J Charles, I E Lundberg, E Paterson, L Ekholm, K Dankó, I Putova, J Vencovsky
Antibodies to the endoplasmic reticulum-resident chaperones calnexin, BiP and Grp94 in patients with rheumatoid arthritis and systemic lupus erythematosus (9 March, 2010) Free
C K Weber, M Haslbeck, M Englbrecht, B Sehnert, D Mielenz, D Graef, J H Distler, H Burkhardt, G Schett, R E Voll, B G Fürnrohr
Anti-ATP synthase autoantibodies alter endothelial cell (EC) survival by disrupting pH regulation in vasculit (9 March, 2010) Free
C Jamin, J-E Alard, J-O Pers, P Youinou
The effects of hydroxychloroquine on antiphospholipid antibody titres in SLE (9 March, 2010) Free
A Broder, C Putterman

B cells

Takayasu's arteritis characterised by disturbances of B cell homeostasis responds to B cell depletion with rituximab (9 March, 2010) Free
B F Hoyer, K Loddenkemper, I M Mumtaz, A Bruns, C Sengler, K-G Hermann, S Maza, R Keitzer, G-R Burmester, F Buttgereit, A Radbruch, F Hiepe
High serum B cell activating factor predicts good clinical response to rituximab in RA: pilot data (9 March, 2010) Free
E M Vital, R Cuthbert, E Hensor, R Parmar, S Dass, D Corscadden, K Henshaw, A Rawstron, F Ponchel, P Emery
The early marginal zone B cell initiated T independent type 2 response resists the proteasome inhibitor bortezomib (9 March, 2010) Free
V Lang, D Mielenz, H Martin Jäck, K Neubert, C Böhm, G Schett, R E Voll, S Meister
IFN signature determines responder status on B cell depletion in rheumatoid arthritis patients (9 March, 2010) Free
S Vosslamber, H G Raterman, M Schreurs, T van der Pouw Kraan, M T Nurmohamed, W F Lems, B A C Dijkmans, A Voskuyl, C Verweij
Molecular and cellular evolution of functional tertiary lymphoid structures in salivary glands of NOD mice (9 March, 2010) Free
M Bombardieri, E Astorri, E Corsiero, S Gabba, F Barone, G Proctor, C Pitzalis
TNFα blockade impairs T cell dependent humoural responses (9 March, 2010) Free
G F Salinas, L De Rycke, T Cantaert, M van de Burg, B Barendregt, P Remans, P Peter Tak, D Baeten
Elevated levels of CD5+ B cells in spondyloarthritis patients (9 March, 2010) Free
T Cantaert, Y Tiersma, C A Ambarus, J E Paramarta, P P Tak, L E De Rycke, D L Baeten
NFAT2 and STAT3 control type 2 cytokines in CD5 B cells (9 March, 2010) Free
Y Renaudineau, S Garaud, J-O Pers, P Youinou
Sjögren's syndrome (SS): are increased serum levels of cytokine FMS-like tyrosine kinase 3 ligand (Flt3L) indicative of lymphoma? (9 March, 2010) Free
G J Tobón, V Devauchelle, P Youinou, J-O Pers
B cell activating factor of the TNF family: δ4BAFF, an alternate-splice isoform that acts as a transcription factor and exaggerates its production in autoimmunity and cancer (9 March, 2010) Free
L Le Pottier, G J Tobón, P Youinou, J-O Pers
The relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis (9 March, 2010) Free
R M Thurlings, M Boumans, J Tekstra, K Vos, D M van Westing, L G van Baarsen, C Bos, K A Kirou, D M Gerlag, M K Crow, C L Verweij, P P Tak
A novel model of murine B cell-mediated proteinuria identical to human minimal change disease (9 March, 2010) Free
A H J Kim, A S Shaw

Bone/cartilage biology

Inflammatory response is modulated by mitochondrial dysfunction in cultured normal human chondrocytes (9 March, 2010) Free
C Vaamonde-García, N Valcarcel-Ares, R Riveiro-Naveira, B Lema, F J Blanco, M J López-Armada
Silencing expression of Ras family GTPase homologues decreases inflammation and joint destruction in experimental arthritis (9 March, 2010) Free
D de Launay, J Vreijling, J R F Abreu, M A van Maanen, M E Sanders, M J Vervoordeldonk, H Oerum, K Fluiter, P P Tak, K A Reedquist
Selective involvement of ERK and JNK MAP kinases in the synovial tissue of patients with early arthritis (9 March, 2010) Free
D de Launay, M G H van de Sande, G P M van de Sande, C A Wijbrandts, P P Tak, K A Reedquist
Proteasome inhibition aggravates tumour necrosis factor-mediated bone resorption (9 March, 2010) Free
T Kireva, K Polzer, K Neubert, S Meister, B Frey, W Baum, J H Distler, G Schett, R E Voll, J Zwerina
SUMO-specific protease 7 (SENP7) regulates matrix metalloproteinase-9 expression in synovial fibroblasts (9 March, 2010) Free
S Strietholt, M A Peters, S Frank, N Pundt, S Ender, G Kollias, T Pap
Involvement of chemokines in the spontaneous ankylosis mouse model: further evidence for the ‘entheseal stress’ hypothesis (9 March, 2010) Free
K Braem, S Carter, C Deroose, F P Luyten, R J Lories
Induction of death receptor ligand-independent apoptosis by endogeneous TIMP3 in mesenchymal cells (9 March, 2010) Free
C Wunrau, D Wendholt, N Pundt, T Pap, B Dankbar
Chondrocytes from arthritic cartilage in a subset of osteoarthritis patients express lower levels of NF_κB-P65: a survival factor against tumour necrosis factor _α-induced cell death
(9 March, 2010) Free
O J Arntz, M B Bennink, P M van der Kraan, W B van den Berg, F A J van de Loo
Anti-interleukin 17A therapy inhibits tumour necrosis factor-mediated bone loss by modulation of T cell balance (9 March, 2010) Free
K Polzer, M Koenders, W Baum, A Patakas, I Mcinnes, L Joosten, G Schett, W van den Berg, J Zwerina
The TRAF6 binding molecule p62/SQSTM1 is a critical regulator of inflammatory bone destruction (9 March, 2010) Free
A Korb, A Hillmann, S Bürgis, G Kollias, S Hermann, M Schäfers, T Pap, T Weide, A Gessner, H Pavenstädt
Inflammatory tissue damage in chronic destructive arthritis is regulated by FHL2 (9 March, 2010) Free
C Cromme, L H Meyer, K Neugebauer, A Korb, C Wunrau, G Kollias, K Redlich, C Will, E M Schnaeker, R Basel-Duby, D Beaten, B Niederreiter, J Bertrand, V Wixler, T Pap
Influence of anti-tumour necrosis factor drugs, tocilizumab and methotrexate on osteoclast differentiation (9 March, 2010) Free
I Perpétuo, J Caetano-Lopes, A Rodrigues, J Polido-Pereira, M Viana Queiroz, J E Fonseca, H Canhão
Bone cell activity influences bone fragility and fracture risk (9 March, 2010) Free
J Caetano-Lopes, I Aleixo, A Rodrigues, I P Perpétuo, D Fernandes, A Lopes, A Pena, A Faustino, M Vale, P M Amaral, J Monteiro, M F Vaz, H Canhão, J E Fonseca
The Role of the WNT inhibitor sclerostin in rheumatoid arthritis (9 March, 2010) Free
C Wehmeyer, A Stratis, T Pap, B Dankbar
Regulation of osteoclast differentiation and function by BiP (9 March, 2010) Free
M Zaiss, N McGowan, J-P David, A Grigoriadis, G Schett, G Panayi, V Corrigall
Systemically delivered glucocorticoid liposomes suppress bone erosion and inhibit osteoclast activation in synovium and bone marrow during experimental murine arthritis (9 March, 2010) Free
W Hofkens, L C Grevers, B Walgreen, T J de Vries, P J M Leenen, V Everts, G Storm, W B van den Berg, P L van Lent
Joint regeneration in newts? Yes, they can! (9 March, 2010) Free
M Geyer, T Borchardt, F Müller-Schrobsdorff, C Schreiyäck, C Müller, A Wietelmann, C Fiehn, U Müller-Ladner, R Dinser
Loss of integrin α2β1 reduces tumour necrosis factor-dependent inflammatory cartilage destruction and matrix metalloproteinase expression through modulating extracellular signal-regulated kinase (9 March, 2010) Free
M A Peters, S Strietholt, D Wendholt, S Frank, A Korb, G Kollias, B Eckes, T Pap
Immune complex-mediated inhibition of osteoclastogenesis: role for the inhibitory Fc γ receptor IIB in bone erosion in antigen-induced arthritis? (9 March, 2010) Free
L C Grevers, P L E M van Lent, A W Sloetjes, T J de Vries, V Everts, W B van den Berg
Methothrexate directly inhibits RANKL expression and osteoclast formation in very early arthritis (9 March, 2010) Free
S Revu, P Neregård, E af Klint, A I Catrina
Syndecan-4 regulates cartilage degradation in osteoarthritis (9 March, 2010) Free
F Echtermeyer, J Betrand, I Meinecke, K Neugebauer, C Herzog, Y J Lee, Y W Song, R Dreier, T Pap
ERK-activated kinase RSK2 protects against inflammatory arthritis-induced bone destruction by opposing the tumour necrosis factor α-mediated inhibition of bone formation (9 March, 2010) Free
C Böhm, M M Zaiss, R Axmann, A Hess, K Engelke, G Kollias, G Schett, J-P David

Fibrosis

Differential pattern of expression of caveolin-1 and AIF-1 in chronic graft-versus-host disease suggests a specific role in the pathogenesis of systemic sclerosis (9 March, 2010) Free
Ilaria Tinazzi, Domenico Biasi, Fabio Benedetti, Chiara Colato, Paul Emery, Francesco Del Galdo
Potential adipokine involvement in systemic sclerosis (9 March, 2010) Free
Klaus Frommer, Massimiliano Vasile, Tim Schmeiser, Oliver Distler, Steffen Gay, Valeria Riccieri, Andreas Günther, Elke Roeb, Ulf Müller-Ladner, Elena Neumann
Analysis of mononuclear cell subsets in dermis and blood of patients with systemic sclerosis by multicolour flow cytometry (9 March, 2010) Free
Thomas Hügle, Venetia Bigley, Tony Holden, Jacob. M. van Laar
Promoter hypermethylation of the anti-fibrotic gene socs-3 by TGFβ as novel mechanism in the pathogenesis of SSc (9 March, 2010) Free
Clara Dees, Alfiya Akhmetshina, Nicole Busch, Angelika Horn, Johannes Gusinde, Astrid Jünge, Steffen Gay, Oliver Distler, Georg Schett, Jörg H W Distler
5-HT release from platelets and activation of 5-HT2B play a crucial role for development of fibrosis in systemic sclerosis (9 March, 2010) Free
Clara Dees, Alfiya Akhmetshina, Nicole Busch, Jochen Zwerina, Michael Bader, Georg Schett, Oliver Distler, Jörg H W Distler
Activation of Hedgehog signalling plays a crucial role in the pathogenesis of systemic sclerosis (9 March, 2010) Free
Angelika Horn, Clara Dees, Alfiya Akhmetshina, Katrin Palumbo, Nicole Busch, Oliver Distler, Georg Schett, Jörg H W Distler
Predicting lung function decline in systemic sclerosis (SSc) (9 March, 2010) Free
S Mittoo, D Robinson, M Hudson, CSRG, M Baron
Micro RNA analysis reveals novel genes in human systemic lupus erythematosus: miR-21 affects PDCD4 expression and regulates aberrant T cell responses (9 March, 2010) Free
E Stagakis, P Verginis, M Nakou, G Bertsias, E Krasoudaki, E Choustoulaki, H Kritikos, D Iliopoulos, D T Boumpas

Genetics and gene regulation

Expression of Tie2 and Ang-1 is related to the development of persistent and erosive disease in patients with early arthritis (9 March, 2010) Free
M G H van de Sande, D de Launay, S Krausz, G P M van de Sande, C A Wijbrandts, P P Tak, K A Reedquist
The Ang-1/Tie2 angiogenic axis is selectively engaged in rheumatoid arthritis (RA) synovial tissue even before ACR criteria of RA are met (9 March, 2010) Free
M G H van de Sande, D de Launay, S Krausz, G P M van de Sande, C A Wijbrandts, P P Tak, K A Reedquist
The CD40 region is associated with multiple autoimmune diseases in the Greek population (9 March, 2010) Free
G N Goulielmos, M Zervou, G Papadopoulos, S Toussa, V Vazgiourakis, D Plant, M Melissourgaki, H Kritikos, D T Boumpas, P Sidiropoulos
Role of the pro-apoptotic pyrin-interacting protein Siva in the pathogenesis of familial Mediterranean fever (9 March, 2010) Free
D Vassou, E Petraki, E Eliopoulos, D Iliopoulos, I Aksentijevich, P Sidiropoulos, D Kardassis, D T Boumpas, G N Goulielmos
miR-155 and miR-34a regulate proinflammatory cytokine production by human monocytes (9 March, 2010) Free
M Kurowska-Stolarska, L Ballantine, B Stolarski, J Hunter, A Hueber, J A Gracie, F Y Liew, I B McInnes
Upregulated SUMO-2/3 expression is involved in the regulation of apoptosis and matrix metalloproteinase expression in rheumatoid arthritis synovial fibroblasts (9 March, 2010) Free
S Frank, S Strietholt, C Wunrau, T Pap, M A Peters
Skewed X-chromosomal inactivation patterns are present in systemic sclerosis and associated with foxp3 expression (9 March, 2010) Free
J Broen, I L M Wolvers-Tettero, L Geurts-van Bon, M C Vonk, M J Coenen, R Lafyatis,, T R D J Radstake, A W Langerak
Genetic variation in promoter sequence of B cell-activating factor gene is associated with increased risk of myositis development (4 April, 2011) Free
M Faustova, P Novota, O Krystufkova, H Hulejova, J Vencovsky
A novel TNFRSF1 gene mutation in a turkish family: report of three cases (4 April, 2011) Free
F Cosan, A Yazici, A Cefle, A Gul
Modulation of gene expression by leflunomide and prednisone during treatment of early rheumatoid arthritis (4 April, 2011) Free
S Soldano, B Villaggio, F Gallo, P Montagna, R Brizzolara, M Cutolo
Defining TNFα-, IFNγ- and IFNγ-induced gene expression profiles in human monocytes to estimate their cytokine-specific impact in inflammatory diseases (4 April, 2011) Free
B Smiljanovic, J R Grün, T Häupl, A Radbruch, A Grützkau
Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon α activity in patients with systemic lupus erythematosus (4 April, 2011) Free
R Salloum, B S Franek, S N Kariuki, L Rhee, R A Mikolaitis, M Jolly, T O Utset, T B Niewold
High throughput sequencing (HTS) provides full repertoire analysis of the B and T cell receptors in humans and mice, both in blood and synovial tissue (4 April, 2011) Free
P L Klarenbeek, P P Tak, M E Doorenspleet, B D C van Schaik, F M Wensveen, L Gottschal, M E Jakobs, I A M Derks, E Eldering, A H C van Kampen, F Baas, N de Vries
Complete T and B cell receptor repertoire analysis in rheumatoid arthritis using high throughput sequencing (4 April, 2011) Free
P L Klarenbeek, M E Doorenspleet, B D C van Schaik, M M Herenius, M E Jakobs, T Cantaert, D L P Baeten, A H C van Kampen, F Baas, P P Tak, N de Vries
Genetic markers in clinical subtype of juvenile idiopathic arthritis (4 April, 2011) Free
P Le Blay, I Touitou, C Daïen, C Jorgensen, C Ludwig, M Rodière
Endogenous retrovirus control is impaired in B cells from patients with systemic lupus erythematosus (4 April, 2011) Free
Y Renaudineau, C Le Dantec, J-O Pers, P Youinou
Single nucleotide polymorphism 25-TGFβ₁ as a possible marker of response to rituximab in rheumatoid arthritis
(4 April, 2011) Free
C I Daïen, S Fabre, C Rittore, S Soler, V Daïen, N Molinari, I Touitou, C Jorgensen
Negative regulation of BIK by the micro RNA125B interferes with macrophage apoptosis in rheumatoid arthritis (4 April, 2011) Free
J Presumey, I Duroux-Richard, S Fabre, Y-M Pers, G Courties, C Jorgensen, F Apparailly
Association between the MMP-12 gene and systemic sclerosis: role of RS2276109 functional polymorphism in the modulation of skin and pulmonary fibrosis (4 April, 2011) Free
M Manetti, L Ibba-Manneschi, C Fatini, S Guiducci, A F Milia, R Giacomelli, S Bombardieri, C Montecucco, R Abbate, G Valentini, M Matucci-Cerinic
Analysis of TNFR2-mediated functions on osteoclast precursor cells (4 April, 2011) Free
S Blüml, N Binder, B Niederreiter, G Superti-Furga, J Smolen, K Redlich

Innate immunity

Rheumatoid arthritis (RA) patients have variable but comparable NLRP3-inflammasome induction to controls (4 April, 2011) Free
C Choulaki, E Petraki, E Choustoulaki, G Goulielmos, D Boumpas, P Sidiropoulos
Immunomodulatory drugs can inhibit the extracellular release of HMGB1 from cultured human monocytes (4 April, 2011) Free
H Schierbeck, H Wähämaa, T Östberg, U Andersson, H Erlandsson Harris
NR4A1 modulates the inflammatory response during murine experimental arthritis (4 April, 2011) Free
C Scholtysek, S Uderhardt, G Schett, G Krönke
Macrophage stimulation by angiopoietins-1 and -2 promotes recruitment and retention of white blood cells at sites of inflammation (4 April, 2011) Free
S Krausz, M E Sanders, P P Tak, K A Reedquist
Complement activation and regulation in early and advanced stage osteoarthritis (4 April, 2011) Free
J L Scott, C R Scanzello, C Dragomir, M K Crow
Interleukin 1β and TLR ligands give enhanced cytokine production by their interaction with HMGB1 (4 April, 2011) Free
H Sigridur Hreggvidsdottir, H Wähämaa, T Östberg, H Schierbeck, A Aveberger, L Klevenvall, U Andersson, H Erlandsson Harris
β₂ integrins control the proinflammatory phenotype of type 1 macrophages and dendritic cells
(4 April, 2011) Free
M H Wenink, K C M Santegoets, R Huijbens, L van Bon, C Volgers, M Weenk, P L C M van Riel, W B van den Berg, T R D J Radstake
Metastasis-Promoting protein S100A4 (MTS1) upregulates production of proinflammatory cytokines via TLR-4 (4 April, 2011) Free
L Senolt, L Cerezo, J Vencovský
Toll-like receptor (TLR-7/9), MYOD88, TIR8, dependent and independent autoantigens (4 April, 2011) Free
B Marklein, Z Konthur, T Häupl, A Cope, M Shlomchik, G Steiner, G Burmester, K Skriner
Modulating TLR responses in systemic sclerosis via heme oxygenase-1 (4 April, 2011) Free
L van Bon, A Scharstuhl, B Pennings, R J F Huijbens, M H Wenink, K C M Santegoets, M Vonk, W van den Berg, F Wagener, T R D J Radstake
Heterogeneous nuclear ribonucleoproteinassociated nucleic acids trigger disease in a rat transfer model of arthritis (4 April, 2011) Free
M Hoffmann, C W Steiner, C Baumann, S Herman, G Steiner
Tumour necrosis factor α in rheumatoid arthritis and osteoarthritis patients in blood serum and synovial fluid (9 March, 2010) Free
I Bulina, D Andersone, A Sochnev, V Lavrentjevs, J Arajs, I Astica, E Sikora, J Zepa, I Jaunalksne, L Kovalchuk
Alarmin interleukin 33 is overexpressed in psoriasis and induces ST2-dependent psoriasis-like dermatitis (9 March, 2010) Free
A J Hueber, A M Miller, D L Asquith, N L Millar, D Gilchrist, A Gracie, I B McInnes
Alarmin S100A8 causes severe cartilage damage in antigen-induced arthritis through TLR4 activation and upregulation of FcεRI and FcεRIV (9 March, 2010) Free
P L E M van Lent, L Grevers, R Schelbergen, A Blom, A Sloetjes, T Vogl, J Roth, W B van den Berg
Mast cells contribute to synovial inflammation in non-psoriatic and psoriatic spondyloarthritis (9 March, 2010) Free
T Noordenbos, N Yeremenko, T Cantaert, C Teitsma, J Canete, M van de Sande, P P Tak, D Baeten
Transient receptor potential (TRP) channels contribute to neutrophil chemotaxis during the inflammatory response (4 April, 2011) Free
O Lindemann, D Umlauf, S Mally, J Bertrand, A Fabian, A Dietrich, A Schwab, T Pap
Toll-like receptor 9 (TLR9) controls B cell differentiation in salivary glands of patients with sjögren’s syndrome (4 April, 2011) Free
C Jamin, T Guerrier, L Le Pottier, A Saraux, P Youinou, J Pers
Targeting siglec-E on murine dendritic cells inhibits antigen presentation and CD4 and CD8 t cell responses (4 April, 2011) Free
M Bax, W Unger, S Kaur Singh, E J McKenzie, M Litjens, J J Garcia-Vallejo, E Saeland, S J van Vliet, P R Crocker, Y van Kooyk
Can mannose-binding lectin explain the course and outcome of pregnancy in rheumatoid arthritis? (4 April, 2011) Free
F E van de Geijn, Y A de Man, M Wuhrer, S P Willemsen, A M Deelder, J M W Hazes, R J E M Dolhain
Regulation of interleukin-1ββ dihydroxyvitamin D3 in human macrophages (4 April, 2011) Free
J D Ji, Y Kim, B Lee, T-H Kim, J-B Jun, D-H Yoo, J H Woo, S J Choi, Y H Lee, J Sohn, G G Song

Novel therapeutic targets

Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus (4 April, 2011) Free
J Humrich, R Undeutsch, L Kloke, G-R Burmester, G Riemekasten
Fms-like tyrosine kinase 3 ligand (FLT3L) levels are elevated in RA synovial fluid (4 April, 2011) Free
M I Ramos, A S F Oliveira, S Aarrass, P P Tak, M C Lebre
Alarmins S100A8 AND S100A9 skew chondrocytes towards a cartilage breakdown phenotype (9 March, 2010) Free
R F P Schelbergen, P L E M van Lent, A B Blom, A Sloetjes, T Vogl, J Roth, W B van den Berg
Pathogenic role of IL-17 in endothelial dysfunction, a link between rheumatoid arthritis and atherosclerosis (4 April, 2011) Free
A Hot, V Lenief, M-A Cazalis, P Miossec
A Tissue-specific NF-κB inhibitor ameliorates inflammatory joint diseases (4 April, 2011) Free
B Sehnert, H Burkhardt, F Nimmerjahn, S Pohle, J Wessels, D Vestweber, J Zwerina, G Schett, S Dübel, R Voll
Antibodies against syndecan-4 reduce cartilage destruction in RA-like disease of htnf transgenic mice (4 April, 2011) Free
A Stratis, K Neugebauer, C Wehmeyer, C Wunrau, N Pundt, G Kollias, F Echtermeyer, T Pap
Improvement of rAAV5 transduction efficiency in fibroblast-like synoviocytes by doxorubicin (4 April, 2011) Free
C J Aalbers, S A Loiler, I de Vries, F Mingozzi, M J Vervoordeldonk, P P Tak
VEGF targeting by active immunisation improves joint inflammation and destruction in a murine model of rheumatoid arthritis (4 April, 2011) Free
E Assier, L Semerano, L Delavallee, D Damotte, G Grouard-Vogel, E Bernier, D Zagury, N Bessis, M C Boissier
IL-23 specific targeting by active immunisation improves inflammation and destruction in a murine model of rheumatoid arthritis (4 April, 2011) Free
E Assier, E Duvallet, R Ratsimandresy, L Delavallee, N Bessis, J F Zagury, M C Boissier
The bacterial effector protein YopM is a selfdelivering immune therapeutic agent that reduces inflammation in rheumatoid arthritis (4 April, 2011) Free
J Bertrand, C Rüther, J Scharnert, M Niedermeier, A Schmidt, T Pap
IL-32γ and streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2
(4 April, 2011) Free
B Heinhuis, M I Koenders, F A van de Loo, P L E M van Lent, S-H Kim, C A Dinarello, L A B Joosten, W B van den Berg
Intravenous immunoglobulin promotes apoptosis of mature human B lymphocytes by using CD22 to modulate their antigen B cell receptor (4 April, 2011) Free
S Hillion, J-F Séité, J-O Pers, P Youinou
Immunological characterisation of hoffa's fat pad in osteoarthritis (4 April, 2011) Free
E Yusuf, K A Marijt, G J V M van Osch, A Zuurmond, V Stoianovic-Susulic, R E M Toes, M Kloppenburg, A Ioan-Facsinay
The micrornas as biomarkers in knee osteoarthritis (4 April, 2011) Free
Y M Pers, F Djouad, I Duroux-Richard, F Apparailly, D Noel, C Jorgensen
Deletion of either CD55 or CD97 ameliorates arthritis (4 April, 2011) Free
R M Hoek, D de Launay, E N Kop, A S Yilmaz-Elis, O Karpus, F Lin, K A Reedquist, J S Verbeek, M E Medof, P P Tak, J Hamann

T cells

MicroRNA-182 promotes clonal expansion of activated T helper cells (9 March, 2010) Free
A-B Stittrich, C Haftmann, A Hegazy, M Floessdorf, J Dong, F Fuhrmann, G Heinz, N Li, Z Fang, A Jahn, R Baumgrass, J Grün, W Chen, T Höfer, M Löhning, H-D Chang, N Rajewsky, A Radbruch, M-F Mashreghi
Elevated expression of the Th17 cytokine interleukin 22 in rheumatoid arthritis (9 March, 2010) Free
M Schramm, J Leipe, H Schulze-Koops, A Skapenko
Disease amelioration in the K/BxN mouse model of spontaneous chronic arthritis after CD8 T cell depletion (9 March, 2010) Free
B R Raposo, A M Água-Doce, J A Pereira da Silva, L Graça, M M Souto-Carneiro
Interleukin10-producing CD4 T cells ameliorate murine lupus in NZB/W F1 mice (9 March, 2010) Free
R Undeutsch, A Papendieck, J Y Humrich, G Riemekasten
Maintenance of T cell Rap1 signalling protects mice against collagen-induced arthritis (9 March, 2010) Free
J R F Abreu, S Krausz, W Dontje, A M Grabiec, D deLaunay, M E Sanders, M J Vervoordeldonk, P P Tak, K A Reedquist
Effects of abatacept on monocytes in patients with rheumatoid arthritis (9 March, 2010) Free
M Bonelli, E Ferner, A Savitskaya, S Blüml, C-W Steiner, E Rath, J S Smolen, C Scheinecker
Severity of T cell subset dysregulation influences the probability of achieving drug-induced remission in early arthritis (9 March, 2010) Free
R Cuthbert, R Parmar, J Nam, E Villeneuve, D Corscadden, K Henshaw, P Emery, F Ponchel
Expansions of interleukin 21-secreting CD4 T helper cells in inflammatory arthritides (9 March, 2010) Free
P L Vieira, M C Lebre, S Aarrass, T Newsom-Davis, P P Tak, G R Screaton
Reduced interleukin 7 serum titres are associated with progression towards rheumatoid arthritis in very early inflammatory arthritis (9 March, 2010) Free
R Cuthbert, V Goëb, E A Horner, S Churchman, L Coates, H Marzo-Ortega, J Nam, E Villeneuve, E Vital, P G Conaghan, P Fardellone, X Le Loët, P Emery, O Vittecoq, F Ponchel
Interleukin (IL)23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for IL22 but not IL21 in autoimmune experimental arthritis (9 March, 2010) Free
A M C Mus, F Cornelissen, P S Asmawidjaja, J P van Hamburg, L Boon, R W Hendriks, E Lubberts
Interleukin 15 triggers differentiation/maturation of Foxp3+ T cells from bone marrow in indoleamine 2,3-dioxygenase (IDO)-dependent manner (9 March, 2010) Free
M Chorazy-Massalska, A Radzikowska, E Warnawin, M Jastrzebska, I Janicka, T Burakowski, D Pawlak, W Rudnicka, P Maldyk, E Kontny, W Maslinski
Th17 cells in autoimmune arthritis (9 March, 2010) Free
J Leipe, M Grunke, C Dechant, C Reindl, U Kerzendorf, H Schulze-Koops, A Skapenko
Molecular mechanisms of peripheral CD25 regulatory T cell (Treg) development (9 March, 2010) Free
I Prots, A Skapenko, P E Lipsky, H Schulze-Koops
Interleukin 21-conditioned dendritic cells promote T cell reactivity through the downregulation of ICOS-L (9 March, 2010) Free
M Kavousanaki, N Orphanos, D T Boumpas, P Verginis
Mesenchymal stem cells participate in the loop leading to amplification of inflammation through secretion of interleukin (IL)6, IL1β and IL8 (9 March, 2010) Free
A Eljaafari, M-L Tartelin, P Miossec
Single injection of antigen-specific regulatory Tr1 lymphocytes protects mice from severe collagen-induced arthritis (9 March, 2010) Free
D Martire, A-L Bonnefont, H Asnagli, N Belmonte, M Jourdin-Boucard, S Rouquier, A Mantello, P B Fall, A Foussat, C Jorgensen, P Louis-Plence
Constitutive co-stimulation by B cells is sufficient to trigger T cell-driven autoimmune disease (9 March, 2010) Free
G Franco Salinas, T Cantaert, M Nolte, E Bettelli, V K Kuchroo, P P Tak, R A Van Lier, D L Baeten
Critical role of protein glycosylation in T cell immunity/autoimmunity (9 March, 2010) Free
T G Szabó, R Palotai, P Antal, I Tokatly, L Tóthfalusi, O Lund, G Nagy, A Falus, E I Buzás
Interleukin 17-producing cells are increased in the peripheral blood of patients with rheumatoid arthritis and are enriched at the site of inflammation (9 March, 2010) Free
N J Gullick, H G Evans, D Jayaraj, B W Kirkham, L S Taams
CCR6 Th17 but not CCR6 Th1 cells cooperate with synovial fibroblasts in a proinflammatory feedback loop in early rheumatoid arthritis (9 March, 2010) Free
J P van Hamburg, P S Asmawidjaja, A M C Mus, O B J Corneth, E M Colin, J M W Hazes, R J E M Dolhain, E Lubberts
Peripheral blood CD4 T cell gene expression profiles as predictive biomarkers in early arthritis (9 March, 2010) Free
A G Pratt, D C Swan, S Richardson, G Wilson, C M U Hilkens, D A Young, J D Isaacs
Identification and function of T cells reactive with citrullinated vimentin in HLA-DRB1*0401 humanised mice and rheumatoid arthritis patients (9 March, 2010) Free
O Snir, M Rieck, K Klich, L Klareskog, J H Buckner, V Malmström
IL-21R deficiency during experimental arthritis increases local expression of inflammatory mediators but protects against joint pathology by suppressing Th17 cells (9 March, 2010) Free
M I Koenders, R J Marijnissen, C Nickerson-Nutter, W B van den Berg
Identification of citrullinated vimentin peptides as T cell epitopes in HLA-DR4 positive RA patients (9 March, 2010) Free
A L Feitsma, E I H van der Voort, K L M C Franken, H Bannoudi, B G Elferink, J W Drijfhout, T W J Huizinga, R R P de Vries, R E M Toes, A Ioan-Facsinay
Activation of the aryl hydrocarbon receptor in vivo primes human T cells for interleukin 22 production and inhibits Th17 cells (9 March, 2010) Free
J-M Ramirez, N C Brembilla, O Sorg, R Chicheportiche, T Matthes, J-M Dayer, J-H Saurat, E Roosnek, C Chizzolini
Immune regulation by peripheral Tregs induced upon homotypic T cell/T cell interactions (9 March, 2010) Free
K Thümmler, J Leipe, A Ramming, I Prots, H Schulze-Koops, A Skapenko
Profiling the t cell repertoire in rheumatoid arthritis (9 March, 2010) Free
L Su
Immune regulation by peripheral Tregs induced upon homotypic T cell/T cell interactions (9 March, 2010) Free
K Thümmler, J Leipe, A Ramming, I Prots, H S-Koops, A Skapenko

Author index

Author index (9 March, 2010) Free

Main menu

Table of contents

March 2010 - Volume 69 - Suppl 2

30th European Workshop for Rheumatology Research

Autoantibodies

B cells

Bone/cartilage biology

Fibrosis

Genetics and gene regulation

Innate immunity

Novel therapeutic targets

Other topics

T cells

Author index

Issue Information

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Table of contents

March 2010 - Volume 69 - Suppl 2

30th European Workshop for Rheumatology Research

Autoantibodies

B cells

Bone/cartilage biology

Fibrosis

Genetics and gene regulation

Innate immunity

Novel therapeutic targets

Other topics

T cells

Author index

Issue Information