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Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT
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  • Published on:
    Long term knee OA trial design: an ounce of prevention is worth a pound of cure
    • Jean-Pierre Pelletier, Professor of Medicine
    • Other Contributors:
      • Johanne Martel-Pelletier, Lukas M. Wildi, and Jean-Pierre Raynauld

    Dear Editor,

    Sawitzke et al (1) reported on the results from the GAIT study assessing the long term effects of 2-year treatment on knee osteoarthritis (OA) symptoms. The findings indicate that the effects of glucosamine hydrochloride (GHCl), chondroitin sulfate (CS), and celecoxib treatment were not better than placebo, although safe and well tolerated.
    The study results are not surprising in view of the original G...

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    Conflict of Interest:
    None declared.