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Extended report
Evidence for treating rheumatoid arthritis to target: results of a systematic literature search
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  • Published on:
    Re:Intensive management of early RA leads to improvements in physical function.
    • Monika Schoels
    • Other Contributors:
      • Rachel Knevel, Daniel Aletaha, Johannes W J Bijlsma, et al

    Dear Editor,

    Thank you for your letter, and the possibility to reply. We fully appreciate the favorable HAQ outcomes of the intensive strategy arm in the TICORA study [1].
    However, based on the systematic literature search for the Treat to Target Initiative, the impact of strategic treatment on functional outcome was controversial: of the four trials that assessed functional outcome[1-4], three [2-4] stated no ben...

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    Conflict of Interest:
    None declared.
  • Published on:
    Intensive management of early RA leads to improvements in physical function.

    Dear Editor,

    Many thanks to Schoels et al for their very helpful systematic literature review of the evidence for treating RA to target [1]. However, I am concerned that the authors' discussion may lead readers to conclude erroneously that there is no evidence that treat to target, intensive management has a beneficial impact on physical function. In their discussion the authors state that 'Functional outcomes, reported...

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    Conflict of Interest:
    None declared.