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Digital ulcers (DUs) cause significant morbidity in systemic sclerosis (SSc), occurring in 50% of patients with the disease.1 Patients report the impact of Raynaud's phenomenon and DU as worse than lung and gastrointestinal problems associated with SSc.2 The Health Assessment Questionnaire (HAQ)3 score is higher in patients with SSc with DU than in those without DU.4 A subset of the Health Assessment Questionnaire Disability Index (HAQ-DI) has been used for determining hand function,5 which is associated with work disability in patients with SSc.6 The purpose of this study was to determine if the HAQ score improved when a DU healed and if it worsened when a DU occurred.
Data were obtained from Actelion Pharmaceuticals Ltd for this post hoc analysis. All patients participating in the RAndomised Placebo-controlled Investigation of Digital ulcers …
Funding Data for this study were from the RAPIDS-1 and RAPIDS-2 trials funded by Actelion Pharmaceuticals Ltd.
Competing interests JP has received payment from Actelion Pharmaceuticals Ltd for consultancy.
Provenance and peer review Not commissioned; externally peer reviewed.
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