Elevated liver enzyme tests among patients with rheumatoid arthritis or psoriatic arthritis treated with methotrexate and/or leflunomide

J R Curtis; T Beukelman; A Onofrei; S Cassell; J D Greenberg; A Kavanaugh; G Reed; V Strand; J M Kremer

doi:10.1136/ard.2008.101378

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Clinical and epidemiological research

Extended report

Elevated liver enzyme tests among patients with rheumatoid arthritis or psoriatic arthritis treated with methotrexate and/or leflunomide

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	Abstract	Full	Pdf
Jan 2009	144	0	119
Feb 2009	114	0	103
Mar 2009	76	0	31
Apr 2009	35	0	38
May 2009	23	0	33
Jun 2009	26	0	26
Jul 2009	36	0	19
Aug 2009	27	0	11
Sep 2009	24	0	19
Oct 2009	32	0	14
Nov 2009	24	0	7
Dec 2009	185	21	137
Jan 2010	158	46	114
Feb 2010	104	28	72
Mar 2010	87	34	71
Apr 2010	72	22	39
May 2010	54	24	36
Jun 2010	83	35	46
Jul 2010	68	18	36
Aug 2010	81	27	31
Sep 2010	109	20	32
Oct 2010	59	27	29
Nov 2010	75	44	54
Dec 2010	66	31	46
Jan 2011	66	13	18
Feb 2011	51	11	11
Mar 2011	67	13	23
Apr 2011	61	14	27
May 2011	55	6	14
Jun 2011	56	14	23
Jul 2011	59	7	10
Aug 2011	59	15	22
Sep 2011	25	7	10
Oct 2011	40	13	17
Nov 2011	64	7	13
Dec 2011	101	7	20
Jan 2012	92	5	7
Feb 2012	72	8	12
Mar 2012	127	10	18
Apr 2012	97	15	14
May 2012	103	7	5
Jun 2012	74	10	10
Jul 2012	85	8	11
Aug 2012	65	4	7
Sep 2012	69	5	7
Oct 2012	93	7	13
Nov 2012	94	12	16
Dec 2012	75	3	2
Jan 2013	91	9	14
Feb 2013	74	7	9
Mar 2013	93	11	10
Apr 2013	88	8	12
May 2013	85	5	12
Jun 2013	55	7	9
Jul 2013	36	4	7
Aug 2013	47	5	8
Sep 2013	56	6	12
Oct 2013	48	7	6
Nov 2013	65	11	9
Dec 2013	40	8	3
Jan 2014	45	5	5
Feb 2014	57	5	8
Mar 2014	69	6	10
Apr 2014	58	4	9
May 2014	40	3	5
Jun 2014	37	5	3
Jul 2014	53	2	0
Aug 2014	44	2	5
Sep 2014	76	4	13
Oct 2014	49	4	5
Nov 2014	36	7	7
Dec 2014	40	4	3
Jan 2015	32	4	5
Feb 2015	49	11	11
Mar 2015	32	7	6
Apr 2015	26	5	8
May 2015	34	9	7
Jun 2015	38	8	8
Jul 2015	41	3	9
Aug 2015	44	1	3
Sep 2015	78	12	16
Oct 2015	39	6	5
Nov 2015	52	7	8
Dec 2015	62	6	8
Jan 2016	61	6	7
Feb 2016	58	6	14
Mar 2016	48	5	10
Apr 2016	43	1	5
May 2016	51	1	4
Jun 2016	38	7	8
Jul 2016	48	3	4
Aug 2016	42	4	6
Sep 2016	61	10	11
Oct 2016	59	12	5
Nov 2016	37	4	4
Dec 2016	45	12	5
Jan 2017	65	16	2
Feb 2017	69	27	8
Mar 2017	65	22	15
Apr 2017	75	15	11
May 2017	85	10	30
Jun 2017	144	15	56
Jul 2017	232	9	51
Aug 2017	200	7	48
Sep 2017	172	6	28
Oct 2017	249	9	23
Nov 2017	216	6	26
Dec 2017	199	6	18
Jan 2018	140	8	18
Feb 2018	193	9	17
Mar 2018	135	14	13
Apr 2018	104	9	4
May 2018	116	14	6
Jun 2018	139	5	5
Jul 2018	164	4	2
Aug 2018	215	7	15
Sep 2018	183	7	12
Oct 2018	186	9	10
Nov 2018	271	11	17
Dec 2018	241	5	7
Jan 2019	190	9	12
Feb 2019	188	13	9
Mar 2019	273	12	9
Apr 2019	192	7	5
May 2019	153	9	7
Jun 2019	116	4	3
Jul 2019	179	3	2
Aug 2019	148	11	6
Sep 2019	157	8	7
Oct 2019	170	11	8
Nov 2019	190	11	8
Dec 2019	185	6	5
Jan 2020	317	10	6
Feb 2020	281	10	8
Mar 2020	197	3	0
Apr 2020	123	4	1
May 2020	143	7	2
Jun 2020	185	9	4
Jul 2020	155	4	2
Aug 2020	184	9	2
Sep 2020	287	9	1
Oct 2020	267	16	7
Nov 2020	234	6	2
Dec 2020	273	8	1
Jan 2021	256	8	5
Feb 2021	347	6	7
Mar 2021	381	13	4
Apr 2021	193	6	4
Total	15834	1369	2433

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