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Rituximab in diffuse cutaneous systemic sclerosis: an open-label clinical and histopathological study
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  • Published on: 18 November 2009
    Comments on the paper by Smith et al.

    Dear Editor,

    I read with interest the article by Smith et al, which provides encouraging data on safety and potential efficacy of rituximab in a subset of patients with diffuse cutaneous systemic sclerosis (DcSSc). It lends support to the concept that B-cell depletion could be a relatively safe and effective strategy DcSSc. The effects on skin thickening differ from those published by Lafyatis et al, indicating a prospec...

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    Conflict of Interest:
    None declared.