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High-resolution MRI for assessment of middle meningeal artery involvement in giant cell arteritis
  1. T A Bley1,2,
  2. J Geiger1,
  3. S Jacobsen3,
  4. O Wieben4,
  5. M Markl1,
  6. P Vaith5,
  7. T Grist2,
  8. M Langer1,
  9. M Uhl1
  1. 1
    Department of Diagnostic Radiology and Medical Physics, University Hospital Freiburg, Freiburg, Germany
  2. 2
    Department of Radiology, University of Wisconsin – Madison, Madison, Wisconsin, USA
  3. 3
    Department of Rheumatology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
  4. 4
    Department of Medical Physics, University of Wisconsin – Madison, Madison, Wisconsin, USA
  5. 5
    Department of Rheumatology and Clinical Immunology, University Hospital Freiburg, Freiburg, Germany
  1. T A Bley, University of Madison – Wisconsin, Department of Radiology, 600 Highland Avenue, Madison, Wisconsin 53792, USA; tbley{at}uwhealth.org

https://doi.org/10.1136/ard.2008.101816

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    Giant cell arteritis (GCA) typically involves the superficial cranial arteries, the aorta and its branches. It has been discussed to which extent the vasculitic changes of the cranial arteries continue into the intracranial region. Autopsy findings have indicated that the characteristic signs of arteritic inflammation of GCA end after crossing the dural border.1 In a recent review of several published cases it was concluded that intracranial/intradural involvement in GCA is rare and represents a small subset of GCA that is non-responsive to corticosteroids and has a fatal course.2

    Contrast-enhanced, high-resolution MRI allows non-invasive assessment of mural inflammation in the extracranial, superficial arteries in giant cell arteritis.3 Here, we report MRI findings suggestive of intracranial vasculitic involvement in patients with GCA. High-resolution MRI of …

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    Footnotes

    • Competing interests: None declared.

    • Ethics approval: Obtained.