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Melanoma inhibitory activity, a biomarker related to chondrocyte anabolism, is reversibly suppressed by proinflammatory cytokines in rheumatoid arthritis
  1. B Vandooren1,2,
  2. T Cantaert1,
  3. M-J van Lierop3,
  4. E Bos3,
  5. L De Rycke1,
  6. E M Veys2,
  7. F De Keyser2,
  8. B Bresnihan4,
  9. F P Luyten5,
  10. P C Verdonk6,
  11. P P Tak1,
  12. A H Boots3,
  13. D Baeten1,2
  1. 1
    Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, The Netherlands
  2. 2
    Department of Rheumatology, Ghent University Hospital, Belgium
  3. 3
    Department of Pharmacology, NV Organon, Oss, The Netherlands
  4. 4
    Department of Rheumatology, St Vincent’s University Hospital, Dublin, Ireland
  5. 5
    Division of Rheumatology, University Hospitals Leuven, Belgium
  6. 6
    Department of Orthopaedic Surgery and Traumatology, Ghent University Hospital, Belgium
  1. D Baeten, Division of Clinical Immunology and Rheumatology, F4-218, Academic Medical Center/University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands; D.L.Baeten{at}amc.uva.nl

Footnotes

  • Competing interests: None declared.

  • Funding: BV is a research assistant for the fund for scientific research Flanders (FWO-Vlaanderen). This research was partially supported by the European Community’s FP6 funding. This publication reflects only the views of the authors. The European Community is not liable for any use that may be made of the information herein. LDeR is supported by a Veni grant from the Dutch Scientific Organization. DB is supported by a Vidi grant from the Dutch Scientific Organization.

  • Ethics approval: All patients gave their written informed consent before entry in the study protocol as approved by the local ethics committee.

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Footnotes

  • Competing interests: None declared.

  • Funding: BV is a research assistant for the fund for scientific research Flanders (FWO-Vlaanderen). This research was partially supported by the European Community’s FP6 funding. This publication reflects only the views of the authors. The European Community is not liable for any use that may be made of the information herein. LDeR is supported by a Veni grant from the Dutch Scientific Organization. DB is supported by a Vidi grant from the Dutch Scientific Organization.

  • Ethics approval: All patients gave their written informed consent before entry in the study protocol as approved by the local ethics committee.

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