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Subluxing arthropathy: an unusual manifestation of the antisynthetase syndrome
  1. O Meyer1,
  2. H Charlanne2,
  3. P Cherin3,
  4. Y Allanore4,
  5. P Coquerelle5,
  6. B Grardel6,
  7. A-M Chamot7,
  8. E Hachulla2
  1. 1
    Department of Rheumatology, D. Diderot University, Bichat Teaching Hospital, AP-HP, Paris, France
  2. 2
    Department of Internal Medicine, Claude Huriez Teaching Hospital, Lille, France
  3. 3
    Department of Internal Medicine, Pitié-Salpêtrière Teaching Hospital, AP-HP, Paris, France
  4. 4
    Department of Rheumatology A, Paris Descartes University, Cochin Teaching Hospital, AP-HP, Paris, France
  5. 5
    Department of Rheumatology, Germon and Gauthier Hospital, Béthune, France
  6. 6
    Rheumatology Private Practice, Arras, France
  7. 7
    Rheumatology Private Practice, Morges, Switzerland
  1. Professor Olivier Meyer, Department of Rheumatology, CHU Bichat, 46 rue Henri Huchard, 75018 Paris France; olivier.meyer{at}

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Antisynthetase syndrome was first described by Marguerie et al as a combination of polymyositis (or at least creatine kinase elevation), diffuse interstitial lung disease and autoantibodies to t-RNA synthetase.1

Joint signs and symptoms occur in up to 90% of patients with polymyositis or dermatomyositis2 and/or antisynthetase syndrome, occasionally as the initial manifestations. They include arthralgia, polyarthritis and deforming arthropathy with subluxation.

To establish a multicentre registry of patients with joint manifestations of antisynthetase syndrome, a standardised form was posted on the CRI (Club Rhumatismes et Inflammation) website (, which is part of the French Society for Rheumatology, with the partnership of the French Society of Internal Medicine.

During a …

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  • Competing interests: None.

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