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Pretreatment serum levels of anti-cyclic citrullinated peptide antibodies are associated with the response to methotrexate in recent-onset arthritis

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  • Funding: The PROMPT study was financed with grants from the Dutch Arthritis Foundation and the Netherlands Organisation for Scientific Research. The BeSt study was financed with grants from the Dutch College of Health Insurances, Schering-Plough BV and Centocor Inc.

  • Competing interests: None.

  • Ethics approval: Ethics committee approval obtained.

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