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The effect of oral or intravenous steroid treatment on glucose metabolism is well known.1 Intra-articular steroid injection (IASI) at the knee joint is a common procedure,2 however there are no studies on the effect of IASI on glucose metabolism. Patients with controlled diabetes (HgA1C<7), using modern versions of blood glucose monitoring devices, with knee pain due to osteoarthritis of the knee (OAK) for more than 3 months without sufficient response to non-steroidal anti-inflammatory drugs (NSAIDs) and physical therapy were offered an IASI of 50 mg of methylprednisolone acetate (MPA) (Pharmacia & Upjohn, Puurs, Belgium) at the knee joint. If they agreed, patients were asked to …
Competing interests: None declared.
Ethics approval: The study was approved by the Helsinki committee of the Nazareth Hospital, and all the patients signed a consent form.
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