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The art of medicine in treating osteoarthritis: I will please
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    Paracetamol and the placebo effect in osteoarthritis trials. The missing link

    Dear Editor,

    Zhang and colleagues reported in a recent metaanalysis of randomised trials that placebo is very effective in the treatment of osteoarthritis (OA), especially for pain, stiffness and self-reported function.[1] In addition Zhang et al. concluded:” Important determinants of the magnitude of effect appear to be the baseline severity, the expected strength of the treatment, the route of delivery and the sample...

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    Conflict of Interest:
    None declared.