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Consistency in assessing the Disease Activity Score-28 in routine clinical practice
  1. C A E Walsh,
  2. R H Mullan,
  3. P B Minnock,
  4. C Slattery,
  5. O FitzGerald,
  6. B Bresnihan
  1. Department of Rheumatology, St Vincent’s University Hospital, Dublin, Ireland
  1. Ceara Walsh, Department of Rheumatology, St Vincent’s University Hospital, Dublin 4, Ireland; cearawalsh{at}

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With the increasing availability of biological therapies for patients with rheumatoid arthritis (RA), the need to include reliable and reproducible clinical measures of disease activity in routine practice has been emphasised.1 Disease Activity Score-28 (DAS28) is validated for use in clinical trials;25 however, it is not known how it performs in a clinical setting.

The aim of this study was to evaluate consistency in the measurement of DAS28, and its individual components, by clinic staff in one centre with different levels of experience. Twelve patients with RA (six per exercise) were assessed for the inter-observer exercises. Five patients were assessed for the intra-observer exercise. Six members of the rheumatology team (two staff rheumatologists, two trainees in rheumatology, …

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