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Crico-thyroid perichondritis leading to sore throat in patients with active adult-onset Still’s disease
  1. Der-Yuan Chen1,
  2. Howard Haw-Chang Lan2,
  3. Tsu-Yi Hsieh1,
  4. Hsin-Hua Chen1,
  5. Joung-Liang Lan1,3
  1. 1Taichung Veterans General Hospital, Taichung, Taiwan
  2. 2Department of Radiology, Taichung Veterans General Hospital and Central Taiwan University of Science and Technology
  3. 3School of Medicine, Taipei Medical University, Taiwan
  1. Correspondence to:
    Dr. Joung-Liang Lan
    MD, Department of Internal Medicine, Taichung Veterans General Hospital, No. 160, Section 3, Taichung-Kang Road, Taichung City 40705, Taiwan; jllan{at}

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A review of 341 adult-onset Still’s disease (AOSD) patients noted that 69% of all reported cases1 and 84% (69/82) of our series2 displayed sore throat early in the disease course. Despite the presence of severe sore throat, physical examinations showed normal findings or only mild pharyngeal infection, and imaging studies (including computed tomography (CT) scans) of the neck were negative.1–4 The lesions responsible for sore throat in active AOSD patients have not yet been explored.

We performed magnetic resonance imaging (MRI) of the larynx5 in 6 active AOSD patients (3 females and 3 males; mean age 33.5 years; table 1) presenting with sore throat and fulfilling the Yamaguchi criteria.6 Our aim was to identify the lesions responsible for sore throat in AOSD patients. Throat swabs for bacterial cultures were negative and serological tests for …

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  • Competing interests: None declared.