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Disease Activity Score 28 (DAS28) using C-reactive protein underestimates disease activity and overestimates EULAR response criteria compared with DAS28 using erythrocyte sedimentation rate in a large observational cohort of rheumatoid arthritis patients in Japan
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  • Published on:
    DAS28-CRP should be evaluated using different criteria from that for DAS28-ESR

    Dear Editor,

    We have read with interest the article recently published by Matsui et al (1). They study a large cohort of patients with rheumatoid arthritisfrom 33 hospitals in Japan and conclude that the modified Disease Activity Score including 28-joint count and using C-reactive protein (DAS28-CRP) gives mean values lower than the same index using ESR (DAS28-ESR). They find a mean difference of 0.72 and state that DAS...

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    Conflict of Interest:
    None declared.