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Palindromic rheumatism is characterised by multiple, episodic and recurrent attacks of arthritis, accompanied by periarticular inflammation without residual joint damage, occurring at irregular intervals and lasting from a few hours to several days.1–3
The definite pathogenesis and disease entity of palindromic rheumatism has not been clarified until now. We investigated the association of rheumatoid arthritis and palindromic rheumatism with regard to genotype by identifying the distribution of human leucocyte antigen (HLA)-DRB1 alleles in patients with palindromic rheumatism and controls in the Korean population.
In all, 110 eligible patients with palindromic rheumatism (53 men and 57 women) were recruited. All enrolled patients met our inclusion criteria, which were based on diagnostic features previously described in the literature. …
Funding: This work was partly supported by a grant from the Korea Health 21 R&D Project, Ministry of Health and Welfare, Republic of Korea (01-PJ3-PG6-01GN11-0002).
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