Inhibition of c-kit tyrosine kinase by imatinib mesylate induces apoptosis in mast cells in rheumatoid synovia: a potential approach to the treatment of arthritis

A Juurikivi; C Sandler; K A Lindstedt; P T Kovanen; T Juutilainen; M J Leskinen; T Mäki; K K Eklund

doi:10.1136/ard.2004.029835

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Inhibition of c-kit tyrosine kinase by imatinib mesylate induces apoptosis in mast cells in rheumatoid synovia: a potential approach to the treatment of arthritis

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	Abstract	Full	Pdf
Jul 2005	69	128	131
Aug 2005	50	112	41
Sep 2005	21	75	28
Oct 2005	29	94	41
Nov 2005	27	80	25
Dec 2005	9	61	36
Jan 2006	11	23	18
Feb 2006	10	13	6
Mar 2006	4	13	13
Apr 2006	4	6	6
May 2006	6	18	16
Jun 2006	16	10	10
Jul 2006	6	9	7
Aug 2006	8	40	25
Sep 2006	11	39	21
Oct 2006	12	47	28
Nov 2006	5	49	30
Dec 2006	4	29	14
Jan 2007	9	49	32
Feb 2007	8	31	25
Mar 2007	8	45	21
Apr 2007	14	7	7
May 2007	22	21	13
Jun 2007	26	20	13
Jul 2007	12	11	8
Aug 2007	13	17	18
Sep 2007	20	19	19
Oct 2007	10	17	7
Nov 2007	10	9	5
Dec 2007	15	9	9
Jan 2008	11	11	5
Feb 2008	13	9	6
Mar 2008	30	11	7
Apr 2008	19	9	4
May 2008	32	10	8
Jun 2008	39	11	8
Jul 2008	21	9	10
Aug 2008	62	11	7
Sep 2008	49	6	3
Oct 2008	40	17	14
Nov 2008	17	4	7
Dec 2008	16	6	7
Jan 2009	14	8	16
Feb 2009	43	7	6
Mar 2009	50	5	5
Apr 2009	16	5	3
May 2009	10	7	4
Jun 2009	32	11	6
Jul 2009	31	6	4
Aug 2009	24	9	3
Sep 2009	23	4	7
Oct 2009	63	6	5
Nov 2009	34	7	8
Dec 2009	102	3	12
Jan 2010	53	6	2
Feb 2010	39	7	5
Mar 2010	25	7	6
Apr 2010	21	13	5
May 2010	40	5	3
Jun 2010	89	9	5
Jul 2010	20	7	7
Aug 2010	102	8	3
Sep 2010	24	12	3
Oct 2010	24	9	4
Nov 2010	29	16	2
Dec 2010	10	6	2
Jan 2011	21	10	2
Feb 2011	17	11	4
Mar 2011	13	12	2
Apr 2011	14	7	6
May 2011	34	5	4
Jun 2011	17	9	4
Jul 2011	13	5	0
Aug 2011	30	5	1
Sep 2011	40	10	4
Oct 2011	46	4	2
Nov 2011	58	14	3
Dec 2011	51	45	10
Jan 2012	48	42	4
Feb 2012	45	40	6
Mar 2012	96	92	17
Apr 2012	81	91	35
May 2012	125	107	44
Jun 2012	208	199	38
Jul 2012	579	553	48
Aug 2012	618	591	44
Sep 2012	635	627	42
Oct 2012	301	296	34
Nov 2012	21	30	10
Dec 2012	9	7	11
Jan 2013	15	8	16
Feb 2013	14	21	13
Mar 2013	15	21	9
Apr 2013	14	12	9
May 2013	16	19	7
Jun 2013	6	15	3
Jul 2013	8	10	6
Aug 2013	18	9	4
Sep 2013	12	11	2
Oct 2013	9	9	6
Nov 2013	13	9	12
Dec 2013	6	9	2
Jan 2014	13	16	10
Feb 2014	15	16	8
Mar 2014	14	13	5
Apr 2014	11	17	5
May 2014	12	17	7
Jun 2014	9	14	4
Jul 2014	26	31	6
Aug 2014	15	15	3
Sep 2014	13	13	15
Oct 2014	4	19	11
Nov 2014	13	13	11
Dec 2014	3	15	10
Jan 2015	4	6	3
Feb 2015	7	2	7
Mar 2015	11	26	7
Apr 2015	17	10	6
May 2015	13	16	2
Jun 2015	13	10	0
Jul 2015	6	8	0
Aug 2015	7	19	5
Sep 2015	14	22	4
Oct 2015	5	10	2
Nov 2015	3	14	6
Dec 2015	7	10	6
Jan 2016	12	10	7
Feb 2016	9	9	2
Mar 2016	10	14	7
Apr 2016	2	15	4
May 2016	16	16	5
Jun 2016	6	22	3
Jul 2016	12	12	7
Aug 2016	11	16	8
Sep 2016	12	21	5
Oct 2016	19	19	9
Nov 2016	9	10	11
Dec 2016	12	17	12
Jan 2017	8	14	7
Feb 2017	2	10	5
Mar 2017	2	19	2
Apr 2017	0	17	6
May 2017	4	21	5
Jun 2017	2	20	7
Jul 2017	14	14	1
Aug 2017	30	16	3
Sep 2017	23	21	2
Oct 2017	26	18	3
Nov 2017	25	21	4
Dec 2017	16	16	2
Jan 2018	22	20	5
Feb 2018	33	22	5
Mar 2018	30	24	3
Apr 2018	30	28	1
May 2018	27	25	3
Jun 2018	40	36	2
Jul 2018	28	28	2
Aug 2018	39	29	7
Sep 2018	26	24	1
Oct 2018	19	19	4
Nov 2018	29	27	2
Dec 2018	20	18	1
Jan 2019	29	25	6
Feb 2019	22	20	3
Mar 2019	24	22	5
Apr 2019	26	27	7
May 2019	19	19	12
Jun 2019	20	20	10
Jul 2019	31	25	13
Aug 2019	26	24	3
Sep 2019	35	29	8
Oct 2019	27	25	6
Nov 2019	31	26	11
Dec 2019	51	44	9
Jan 2020	38	38	8
Feb 2020	35	28	5
Mar 2020	17	17	4
Apr 2020	14	12	8
May 2020	8	8	1
Jun 2020	18	14	10
Jul 2020	19	17	3
Aug 2020	17	13	6
Sep 2020	51	44	1
Oct 2020	33	29	9
Nov 2020	38	28	8
Dec 2020	31	27	11
Jan 2021	16	16	6
Feb 2021	27	21	9
Mar 2021	28	28	7
Apr 2021	8	8	4
May 2021	16	14	7
Jun 2021	31	31	9
Jul 2021	15	15	9
Aug 2021	17	16	5
Sep 2021	21	19	10
Oct 2021	47	45	28
Nov 2021	32	24	26
Dec 2021	24	24	7
Jan 2022	45	45	8
Feb 2022	22	20	5
Mar 2022	82	82	8
Apr 2022	37	37	10
May 2022	40	40	16
Jun 2022	37	35	10
Jul 2022	25	22	5
Aug 2022	32	33	7
Sep 2022	27	25	17
Oct 2022	43	38	9
Nov 2022	21	21	5
Dec 2022	24	22	5
Jan 2023	22	21	5
Feb 2023	40	37	4
Mar 2023	35	33	1
Apr 2023	23	17	6
Total	7379	6773	2070

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