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Anti-C1q antibodies in renal and non-renal SLE
  1. D J Armstrong1,
  2. A D Crockard2,
  3. E M Whitehead3,
  4. A L Bell4
  1. 1United Hospitals Trust, Bush Road, Antrim, UK
  2. 2Regional Immunology Laboratory, Royal Victoria Hospital, Belfast, UK
  3. 3United Hospitals Trust, Bush Road, Antrim, UK
  4. 4Queen’s University Belfast, Belfast, UK
  1. Correspondence to:
    Dr D J Armstrong
    Department of Rheumatology, Musgrave Park Hospital, Stockman’s Lane, Belfast, Northern Ireland BT9 7JB, UK;

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We read with interest the report of Marto et al1 on the occurrence of anti-C1q antibodies in systemic lupus erythematosus (SLE), particularly their finding of anti-C1q in 39.8% of patients with SLE without renal disease, 27.3% of whom went on to develop nephritis.

We recently tested for anti-C1q antibodies using an enzyme linked immunosorbent assay (ELISA) kit (Buhlmann Laboratories, Basel) in the sera …

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