Proteolysis of serum amyloid A and AA amyloid proteins by cysteine proteases: cathepsin B generates AA amyloid proteins and cathepsin L may prevent their formation

C Röcken; R Menard; F Bühling; S Vöckler; J Raynes; B Stix; S Krüger; A Roessner; T Kähne

doi:10.1136/ard.2004.030429

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Proteolysis of serum amyloid A and AA amyloid proteins by cysteine proteases: cathepsin B generates AA amyloid proteins and cathepsin L may prevent their formation

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	Abstract	Full	Pdf
May 2005	48	97	72
Jun 2005	43	91	37
Jul 2005	23	41	15
Aug 2005	19	38	17
Sep 2005	16	38	13
Oct 2005	14	27	9
Nov 2005	15	22	6
Dec 2005	6	12	1
Jan 2006	7	4	3
Feb 2006	7	5	5
Mar 2006	5	7	6
Apr 2006	7	6	4
May 2006	6	8	4
Jun 2006	13	6	3
Jul 2006	5	9	7
Aug 2006	0	14	12
Sep 2006	9	14	9
Oct 2006	3	19	13
Nov 2006	4	17	18
Dec 2006	6	14	9
Jan 2007	7	21	16
Feb 2007	3	14	8
Mar 2007	3	23	8
Apr 2007	5	8	6
May 2007	9	9	0
Jun 2007	5	9	6
Jul 2007	4	7	5
Aug 2007	6	12	5
Sep 2007	6	8	8
Oct 2007	6	4	4
Nov 2007	4	6	2
Dec 2007	6	3	1
Jan 2008	5	9	5
Feb 2008	2	4	1
Mar 2008	9	5	6
Apr 2008	3	5	7
May 2008	12	4	3
Jun 2008	18	6	6
Jul 2008	12	1	2
Aug 2008	18	1	0
Sep 2008	15	1	2
Oct 2008	9	4	1
Nov 2008	5	1	0
Dec 2008	4	3	2
Jan 2009	6	3	0
Feb 2009	10	5	2
Mar 2009	17	8	2
Apr 2009	9	7	8
May 2009	8	2	2
Jun 2009	15	0	8
Jul 2009	15	1	3
Aug 2009	4	3	3
Sep 2009	3	4	1
Oct 2009	19	3	4
Nov 2009	16	4	3
Dec 2009	34	0	5
Jan 2010	10	1	2
Feb 2010	16	0	2
Mar 2010	10	4	3
Apr 2010	7	5	3
May 2010	26	3	1
Jun 2010	15	3	4
Jul 2010	6	5	4
Aug 2010	24	2	2
Sep 2010	15	5	1
Oct 2010	16	8	5
Nov 2010	14	2	0
Dec 2010	8	6	1
Jan 2011	18	3	0
Feb 2011	20	13	3
Mar 2011	18	6	3
Apr 2011	12	2	0
May 2011	24	1	0
Jun 2011	16	4	2
Jul 2011	10	5	0
Aug 2011	21	6	0
Sep 2011	16	7	0
Oct 2011	11	2	0
Nov 2011	17	18	4
Dec 2011	14	21	7
Jan 2012	26	15	6
Feb 2012	14	16	3
Mar 2012	13	19	10
Apr 2012	16	14	9
May 2012	16	23	7
Jun 2012	17	24	5
Jul 2012	12	21	5
Aug 2012	4	12	3
Sep 2012	20	16	8
Oct 2012	40	27	10
Nov 2012	39	14	9
Dec 2012	33	12	10
Jan 2013	35	12	10
Feb 2013	14	14	5
Mar 2013	9	6	6
Apr 2013	12	15	8
May 2013	14	8	6
Jun 2013	4	5	3
Jul 2013	14	14	11
Aug 2013	9	8	7
Sep 2013	13	3	1
Oct 2013	12	6	5
Nov 2013	13	2	2
Dec 2013	5	19	5
Jan 2014	4	9	3
Feb 2014	21	7	7
Mar 2014	23	14	8
Apr 2014	8	6	11
May 2014	4	18	3
Jun 2014	4	6	2
Jul 2014	89	10	4
Aug 2014	8	11	6
Sep 2014	4	5	1
Oct 2014	4	6	1
Nov 2014	5	8	8
Dec 2014	5	5	4
Jan 2015	8	7	8
Feb 2015	2	4	5
Mar 2015	2	6	2
Apr 2015	18	5	6
May 2015	5	4	3
Jun 2015	1	6	1
Jul 2015	4	2	1
Aug 2015	3	5	5
Sep 2015	16	8	2
Oct 2015	8	8	2
Nov 2015	6	8	11
Dec 2015	4	8	1
Jan 2016	7	4	3
Feb 2016	10	5	3
Mar 2016	16	5	8
Apr 2016	5	0	3
May 2016	11	9	3
Jun 2016	8	3	3
Jul 2016	8	2	1
Aug 2016	9	6	1
Sep 2016	22	11	3
Oct 2016	15	7	3
Nov 2016	8	8	6
Dec 2016	10	12	4
Jan 2017	11	7	5
Feb 2017	4	4	1
Mar 2017	0	12	4
Apr 2017	5	12	1
May 2017	5	29	7
Jun 2017	13	16	1
Jul 2017	24	24	1
Aug 2017	28	22	3
Sep 2017	17	17	2
Oct 2017	27	25	4
Nov 2017	19	17	1
Dec 2017	31	31	2
Jan 2018	26	26	3
Feb 2018	39	29	12
Mar 2018	15	13	6
Apr 2018	17	17	5
May 2018	10	9	9
Jun 2018	15	15	2
Jul 2018	28	14	7
Aug 2018	16	14	5
Sep 2018	13	9	5
Oct 2018	4	4	2
Nov 2018	14	10	5
Dec 2018	37	37	2
Jan 2019	31	28	3
Feb 2019	12	13	3
Mar 2019	7	5	5
Apr 2019	16	14	7
May 2019	9	9	4
Jun 2019	11	11	10
Jul 2019	13	13	5
Aug 2019	20	18	3
Sep 2019	8	8	6
Oct 2019	21	15	4
Nov 2019	13	10	4
Dec 2019	16	13	6
Jan 2020	12	12	5
Feb 2020	6	6	5
Mar 2020	13	7	12
Apr 2020	7	7	6
May 2020	8	8	2
Jun 2020	13	13	4
Jul 2020	13	11	7
Aug 2020	8	7	7
Sep 2020	21	15	6
Oct 2020	16	16	6
Nov 2020	23	13	9
Dec 2020	9	5	1
Jan 2021	12	12	8
Feb 2021	7	7	4
Mar 2021	15	10	4
Apr 2021	12	10	2
May 2021	21	17	9
Jun 2021	61	61	10
Jul 2021	21	21	5
Aug 2021	12	12	11
Sep 2021	16	16	13
Oct 2021	17	13	20
Nov 2021	31	30	21
Dec 2021	21	21	11
Jan 2022	19	17	3
Feb 2022	19	13	2
Mar 2022	20	14	10
Apr 2022	22	20	9
May 2022	37	44	17
Jun 2022	37	36	13
Jul 2022	23	17	2
Aug 2022	23	19	4
Sep 2022	37	33	12
Oct 2022	28	26	10
Nov 2022	18	11	7
Dec 2022	11	11	3
Jan 2023	17	13	7
Feb 2023	37	33	2
Mar 2023	28	23	5
Apr 2023	11	10	10
May 2023	15	7	8
Jun 2023	16	10	4
Jul 2023	10	6	5
Aug 2023	2	2	4
Sep 2023	18	6	6
Oct 2023	5	5	0
Nov 2023	17	9	1
Dec 2023	44	2	2
Jan 2024	23	0	0
Feb 2024	34	0	0
Mar 2024	95	0	0
Total	3397	2709	1244

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