Tumour necrosis factor blockers do not increase overall tumour risk in patients with rheumatoid arthritis, but may be associated with an increased risk of lymphomas

P Geborek; A Bladström; C Turesson; A Gulfe; I F Petersson; T Saxne; H Olsson; L T H Jacobsson

doi:10.1136/ard.2004.030528

Article metrics

Extended report

Tumour necrosis factor blockers do not increase overall tumour risk in patients with rheumatoid arthritis, but may be associated with an increased risk of lymphomas

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	Abstract	Full	Pdf
Feb 2005	175	0	314
Mar 2005	54	0	178
Apr 2005	188	341	508
May 2005	121	420	399
Jun 2005	88	154	196
Jul 2005	42	102	68
Aug 2005	40	92	57
Sep 2005	37	104	57
Oct 2005	41	107	64
Nov 2005	54	99	57
Dec 2005	26	82	37
Jan 2006	30	37	45
Feb 2006	34	41	42
Mar 2006	24	42	43
Apr 2006	12	28	22
May 2006	24	95	90
Jun 2006	38	64	81
Jul 2006	19	68	68
Aug 2006	28	65	61
Sep 2006	23	59	68
Oct 2006	13	83	83
Nov 2006	23	70	71
Dec 2006	38	71	53
Jan 2007	40	71	70
Feb 2007	24	81	67
Mar 2007	24	59	59
Apr 2007	44	43	61
May 2007	42	37	42
Jun 2007	28	21	20
Jul 2007	35	21	33
Aug 2007	30	18	24
Sep 2007	42	33	48
Oct 2007	25	30	43
Nov 2007	26	21	30
Dec 2007	29	35	33
Jan 2008	28	32	33
Feb 2008	42	27	43
Mar 2008	37	28	40
Apr 2008	34	41	46
May 2008	19	22	33
Jun 2008	32	13	14
Jul 2008	37	18	21
Aug 2008	33	19	26
Sep 2008	84	18	23
Oct 2008	26	11	24
Nov 2008	16	9	20
Dec 2008	16	11	13
Jan 2009	16	6	10
Feb 2009	32	12	23
Mar 2009	33	31	41
Apr 2009	31	21	33
May 2009	36	19	27
Jun 2009	45	7	19
Jul 2009	30	16	17
Aug 2009	58	9	20
Sep 2009	42	25	23
Oct 2009	47	18	20
Nov 2009	42	10	19
Dec 2009	42	2	18
Jan 2010	44	12	15
Feb 2010	23	12	23
Mar 2010	53	12	15
Apr 2010	18	15	18
May 2010	21	9	17
Jun 2010	42	9	11
Jul 2010	19	10	16
Aug 2010	26	12	15
Sep 2010	21	12	9
Oct 2010	53	20	24
Nov 2010	40	36	34
Dec 2010	14	8	8
Jan 2011	43	15	18
Feb 2011	20	19	23
Mar 2011	29	15	23
Apr 2011	38	8	13
May 2011	19	5	7
Jun 2011	22	9	15
Jul 2011	21	10	11
Aug 2011	26	5	11
Sep 2011	32	1	9
Oct 2011	31	3	7
Nov 2011	33	9	17
Dec 2011	36	14	28
Jan 2012	42	11	17
Feb 2012	31	10	13
Mar 2012	38	5	16
Apr 2012	21	8	19
May 2012	30	19	16
Jun 2012	34	8	17
Jul 2012	44	7	18
Aug 2012	35	9	19
Sep 2012	24	7	14
Oct 2012	42	16	31
Nov 2012	42	13	24
Dec 2012	29	6	24
Jan 2013	58	12	19
Feb 2013	55	20	28
Mar 2013	53	21	21
Apr 2013	47	11	16
May 2013	40	13	12
Jun 2013	29	7	13
Jul 2013	37	10	19
Aug 2013	27	7	16
Sep 2013	27	15	14
Oct 2013	32	11	18
Nov 2013	28	7	12
Dec 2013	26	6	10
Jan 2014	27	3	7
Feb 2014	31	5	5
Mar 2014	24	11	15
Apr 2014	26	14	14
May 2014	34	11	13
Jun 2014	23	9	10
Jul 2014	36	11	14
Aug 2014	20	9	7
Sep 2014	27	7	5
Oct 2014	23	15	12
Nov 2014	30	6	7
Dec 2014	13	11	9
Jan 2015	16	7	8
Feb 2015	31	13	12
Mar 2015	37	11	8
Apr 2015	20	9	4
May 2015	22	12	14
Jun 2015	31	3	3
Jul 2015	20	4	4
Aug 2015	12	9	7
Sep 2015	38	10	7
Oct 2015	25	9	9
Nov 2015	9	4	4
Dec 2015	48	6	7
Jan 2016	36	8	9
Feb 2016	30	9	8
Mar 2016	29	7	8
Apr 2016	22	9	11
May 2016	33	15	9
Jun 2016	42	7	21
Jul 2016	23	4	5
Aug 2016	24	7	13
Sep 2016	27	11	13
Oct 2016	34	8	19
Nov 2016	28	4	8
Dec 2016	25	13	12
Jan 2017	28	5	5
Feb 2017	12	35	8
Mar 2017	15	19	4
Apr 2017	14	27	8
May 2017	20	17	11
Jun 2017	23	38	6
Jul 2017	53	45	7
Aug 2017	48	31	13
Sep 2017	34	26	25
Oct 2017	66	48	18
Nov 2017	109	95	12
Dec 2017	215	207	5
Jan 2018	195	187	55
Feb 2018	103	92	8
Mar 2018	134	124	8
Apr 2018	84	64	6
May 2018	85	72	43
Jun 2018	46	42	13
Jul 2018	25	17	7
Aug 2018	59	51	5
Sep 2018	90	86	4
Oct 2018	80	62	4
Nov 2018	114	101	6
Dec 2018	69	61	5
Jan 2019	57	54	23
Feb 2019	63	58	14
Mar 2019	58	39	16
Apr 2019	39	31	9
May 2019	15	7	10
Jun 2019	18	8	20
Jul 2019	22	16	15
Aug 2019	16	12	8
Sep 2019	10	10	8
Oct 2019	19	14	8
Nov 2019	24	14	14
Dec 2019	23	15	5
Jan 2020	21	17	7
Feb 2020	30	28	77
Mar 2020	30	22	16
Apr 2020	20	20	12
May 2020	23	19	4
Jun 2020	22	20	12
Jul 2020	25	14	7
Aug 2020	23	14	16
Sep 2020	30	25	10
Oct 2020	16	16	11
Nov 2020	26	19	14
Dec 2020	16	12	13
Jan 2021	19	15	28
Feb 2021	35	27	52
Mar 2021	42	42	9
Apr 2021	30	29	8
May 2021	34	34	5
Jun 2021	31	31	5
Jul 2021	26	26	18
Aug 2021	16	14	8
Sep 2021	28	27	5
Oct 2021	35	29	18
Nov 2021	17	13	20
Dec 2021	15	9	6
Jan 2022	27	24	83
Feb 2022	39	32	37
Mar 2022	27	23	17
Apr 2022	23	17	6
May 2022	30	28	27
Jun 2022	69	51	29
Jul 2022	28	26	2
Aug 2022	29	31	11
Sep 2022	36	32	25
Oct 2022	47	33	12
Nov 2022	29	21	5
Dec 2022	37	25	9
Jan 2023	44	39	139
Feb 2023	60	46	13
Mar 2023	60	58	5
Apr 2023	24	14	4
May 2023	20	18	13
Jun 2023	17	13	7
Jul 2023	26	20	11
Aug 2023	21	15	8
Sep 2023	20	16	11
Oct 2023	57	47	4
Nov 2023	73	72	7
Dec 2023	260	62	2
Jan 2024	185	15	91
Feb 2024	59	15	3
Mar 2024	146	18	2
Total	9178	7132	6352

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