Therapeutic drug monitoring of A77 1726, the active metabolite of leflunomide: serum concentrations predict response to treatment in patients with rheumatoid arthritis

E N van Roon; T L T A Jansen; M A F J van de Laar; M Janssen; J P Yska; R Keuper; P M Houtman; J R B J Brouwers

doi:10.1136/ard.2004.025205

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Therapeutic drug monitoring of A77 1726, the active metabolite of leflunomide: serum concentrations predict response to treatment in patients with rheumatoid arthritis

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E N van Roon Department of Clinical Pharmacy and Clinical Pharmacology, Medisch Centrum Leeuwarden, Leeuwarden, Netherlands PubMed articles Google scholar articles
T L T A Jansen Department of Rheumatology, Medisch Centrum Leeuwarden PubMed articles Google scholar articles
M A F J van de Laar Department of Rheumatology, Medisch Spectrum Twente and University of Twente, Enschede, Netherlands PubMed articles Google scholar articles
M Janssen Department of Rheumatology, Rijnstate Hospital, Arnhem, Netherlands PubMed articles Google scholar articles
J P Yska Department of Clinical Pharmacy and Clinical Pharmacology, Medisch Centrum Leeuwarden, Leeuwarden, Netherlands PubMed articles Google scholar articles
R Keuper Department of Clinical Pharmacy and Clinical Pharmacology, Medisch Centrum Leeuwarden, Leeuwarden, Netherlands PubMed articles Google scholar articles
P M Houtman Department of Rheumatology, Medisch Centrum Leeuwarden PubMed articles Google scholar articles
J R B J Brouwers Groningen University Institute for Drug Exploration (GUIDE), Subdivision Pharmacotherapy and Pharmaceutical Care, Netherlands PubMed articles Google scholar articles

Correspondence to:
Mr E N van Roon
Department of Clinical Pharmacy and Pharmacology, Medical Centre Leeuwarden, PO Box 888, 8901 BR Leeuwarden, Netherlands; e.n.van.roonznb.nl

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Citation

van Roon EN, Jansen TLTA, van de Laar MAFJ, et al

Therapeutic drug monitoring of A77 1726, the active metabolite of leflunomide: serum concentrations predict response to treatment in patients with rheumatoid arthritis

Annals of the Rheumatic Diseases 2005;64:569-574.

Publication history

Accepted August 12, 2004
First published September 2, 2004.

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January 09, 2022

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