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Non-Hodgkin’s lymphoma in systemic lupus erythematosus
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- Published on: 13 April 2016
- Published on: 13 April 2016SLE and NHL - Is there a common genetic link?Show More
Dear Editor,
An association has been made between systemic lupus erythematosus (SLE) and NHL. A common genetic aetiology is suggested by the observation of a marked over representation of lymphoma cases in families with SLE. Likewise, families have been described with both lymphoma and SLE. A tumour suppressor gene PTEN may link the two disorders via a defective apoptosis pathway to eliminate hyperactive B and T cells...
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None declared.