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Usefulness of glycosylated ferritin in atypical presentations of adult onset Still’s disease
  1. M A Hamidou1,
  2. M Denis2,
  3. S Barbarot3,
  4. D Boutoille4,
  5. C Belizna1,
  6. G Le Moël5
  1. 1Department of Internal Medicine, Hôtel-Dieu Hospital, Nantes, France
  2. 2Biochemistry Laboratory, Hôtel-Dieu Hospital, Nantes, France
  3. 3Department of Dermatology, Hôtel-Dieu Hospital, Nantes, France
  4. 4Department of Infectious Diseases, Hôtel-Dieu Hospital, Nantes, France
  5. 5Biochemistry A Laboratory, Bichat Hospital, Paris, France
  1. Correspondence to:
    Dr M Hamidou
    Service de Médecine Interne, Hôtel-Dieu, Place Alexis Ricordeau, Nantes, 44035 France;

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Many diseases, such as infections, neoplasia, or immune diseases, can mimic adult onset Still’s disease (AOSD).1,2 Atypical forms are not so rare, and the search for a diagnosis marker is warranted. Recently, the usefulness of low serum glycosylated ferritin (GF) was suggested.3–5


An 80 year old woman presented with 4 weeks’ fever, myalgias, polyarthritis, and sore throat. Clinical examination disclosed a fixed generalised maculopapular rash, arthritis of wrists and ankles, and spleen enlargement. C reactive protein was 150 mg/l, haemoglobin level 80 g/l, white blood count 30×109/l with 90% polymorphonuclear neutrophils, 10% lymphocytes, and 600×109/l platelets. Transaminases were twice the normal value (2N). Ferritinaemia was 40 000 μg/l (normal …

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